Flashcards in Disorders of Growth 1 and 2 Deck (20):
What is a neoplasm?
Abnormal mass of tissue
What is neoplasia?
What is the difference between benign and malignant tumours?
Benign - pushes other tissues
Malignant - invades other tissues and can mets
How do malignant tumours spread?
Lymphatic, blood, transcoelmic, epithelium
What is the benign name
What is the malignant name
Benign - oma
Malignant - sarcoma
What is Leukaemia
Neoplastic proliferation of stem cells
Neoplastic calls spill over into blood stream
What is lymphoma ?
Lymphoid tissue cell proliferation
What is Hodgkin's disease?
Mix of cells including reed
What is Non-Hodgkin's lymphoma?
Lacks cellular mix
What is teratoma?
From totipotential cells, producing tissues .. Teeth hair
What are the precursors of malignant rumours?
Lesions with an increased risk of invasive tumour
Can be non-neoplastic and neoplastic
What are the non-neoplastic examples?
Chronic inflammation, cirrhosis of the liver, chronic ulcerative colitis, xeroderma pigmentosum
What is chronic inflammation non-neoplastic?
Varicose leg ulcers leading to skin cancer
What is cirrhosis of the liver non-neoplastic?
What is chronic ulcerative colitis non-neoplastic?
Large intestine adenocarcinoma
What is xeroderma pigmentosum non-neoplastic ?
Squamous cell carcinoma skin
What is familiar polyposis coli neoplasia ?
Autosomal dominant, 1000 adenoma of large intestine, carcinoma inevitable
What is intra-epithelial neoplasia?
Nuclear changed of carcinoma without breaching basement membrane - "dysplasia"
What are some effects of malignant tumours ?
All the physical activities of benign, tissue destruction, secondary infection