Disorders of Growth 1 and 2 Flashcards Preview

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Flashcards in Disorders of Growth 1 and 2 Deck (20):
1

What is a neoplasm?

Abnormal mass of tissue

2

What is neoplasia?

Neoplasm formed

3

What is the difference between benign and malignant tumours?

Benign - pushes other tissues
Malignant - invades other tissues and can mets

4

How do malignant tumours spread?

Local/ direct
Lymphatic, blood, transcoelmic, epithelium

5

What is the benign name
What is the malignant name

Benign - oma
Malignant - sarcoma

6

What is Leukaemia

Neoplastic proliferation of stem cells
Neoplastic calls spill over into blood stream

7

What is lymphoma ?

Lymphoid tissue cell proliferation

8

What is Hodgkin's disease?

Mix of cells including reed

9

What is Non-Hodgkin's lymphoma?

Lacks cellular mix

10

What is teratoma?

From totipotential cells, producing tissues .. Teeth hair

11

What are the precursors of malignant rumours?

Lesions with an increased risk of invasive tumour
Can be non-neoplastic and neoplastic

12

What are the non-neoplastic examples?

Chronic inflammation, cirrhosis of the liver, chronic ulcerative colitis, xeroderma pigmentosum

13

What is chronic inflammation non-neoplastic?

Varicose leg ulcers leading to skin cancer

14

What is cirrhosis of the liver non-neoplastic?

Hepatocellular carcinoma

15

What is chronic ulcerative colitis non-neoplastic?

Large intestine adenocarcinoma

16

What is xeroderma pigmentosum non-neoplastic ?

Squamous cell carcinoma skin

17

What is familiar polyposis coli neoplasia ?

Autosomal dominant, 1000 adenoma of large intestine, carcinoma inevitable

18

What is intra-epithelial neoplasia?

Nuclear changed of carcinoma without breaching basement membrane - "dysplasia"

19

What are some effects of malignant tumours ?

All the physical activities of benign, tissue destruction, secondary infection

20

What is cachexia?

Severe weight loss from increased metabolic rate - associated with malignant tumours