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Pathology > Thrombosis > Flashcards

Flashcards in Thrombosis Deck (17):
1

Where my thrombi form?

Lumen of the heart - MI
Arteries - ischaemic and embolism
Veins - lines of zahn / DVT
Capillaries - disseminated coagulation

2

What are the triggers of thrombosis ?

Infections, septicaemia, malaria, neoplasms, liver disease

3

What's promotes thrombosis?

Abnormalities of the vessel wall, blood flow and blood constituents

4

What causes abnormalities of the vessel wall?

Atheroma in arteries
MI in heart
Trauma, inflam in veins
Inflam in capillaries

5

What causes abnormalities in the blood flow?

Arteries - turbulence, aneurysms, plaques, spasm
Heart - atrial fibrillation, aneurysms
Veins - local problem

6

What causes abnormalities of the blood constituents?

Multiple myeloma, increased viscosity

7

What is an embolism?

The transport of abnormal marital (solid liquid gas) by the blood stream and it's impacting blood vessel

8

What are the types of emboli?

Thrombi, fat, gas, tumour, infection, vegetations, atheroma

9

What is shock?

Significant systemic reduction in tissue perfusion, resulting in decreased tissue oxygen and nutrients removed - tissue injury

10

What is hypovolaemic shock?

Haemorrhage - severe burns

11

What is cardiogenic shock?

Large acute MI - other cardiac disease

12

What is septic shock ?

Endotoxins gram -bacteria, exotoxin gram +

13

What is anaphylactic shock?

Allergic reaction

14

What is neurogenic shock?

Spinal cord trauma

15

What is obstructive shock?

Cardiac tamponade, PE

16

What are the clinical features of shock?

Hypotension, increased HR, unstable resp rate, decreased urine, hypoxia, anxiety, agitation

17

What is thrombosis ?

The formation of a solid or semi-solid mass from the constituents of the blood