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Flashcards in drug reactions Deck (45):
1

Cardio - what drugs cause flushing?

Vancomycin, Adenosine, Niacin, Ca channel blockers

2

Cardio - coronary vasospasm

Cocaine, sumatriptan, ergot alkaloids

3

Cardio - Torsades

Class III (i.e sotalol) and class IA (i.e. quinidine), antiarrhthamics, macrolide antibiotics, antipsychotics, TCAs

4

Endocrin -hot flashes

tamoxifen, clomiphene

5

Endocrin - hyperglycemia

Tacrolimus, Protease inhibitors, Niacin, HCTZ, Beta blockers (because remember beta stimulation causes an increase in insulin), Corticosteroids.

6

Endocrin - hypothyroid

lithium, amiodarone, sulfonamides

7

Endocrin -- Acute cholestatic hepatitis, jaundice

Erythromycin

8

Endocrin - Diarrhea

Metformin, Erythromycin, Cochicine, Orlistat, Acarbose (might excite colon on accident)

9

Endocrin - focal to massive hepatic necrosis

Halothane, Amanita phalloides (death cap mushroom), Valproic acid, Acetaminophen (HAVAc on the liver)

10

Endocrin -hepatitis

Isoniazid (INH)

11

Endocrin -Pancreatitis -

Didansosine, Corticosteroids, Alcohol, Valproic acid, Azathioprine, Diuretics (furosemide, HCTZ). (Drugs Causing A Violent Abdominal Distress)

12

pseudomembranou colitis

Clindamycin, ampicillin, cephalosporins

13

hematologic - (A)granulocytosis

Dapsone, Clozapine, Carbamazepine, Colchicine, Methimazole, Propylthiouracil (Drugs CCCrush Myeloblasts and Promyelocytes)

14

hematologic - Aplastic Anemia

Carbamazepine, Methimazole, NSAIDS, Benzene, Chloramphenicol, Propylthiouracil (Can't Make New Blood Cells Properly)

15

hematologic - Direct Coombs positive hemolytic anemia

Methyldopa, penicillin

16

hematologic - gray baby

chloramphenicol

17

hematologic- Hemolysis in G6PDH

INH, Sulfonamides, Dapsone, Primaquine, Aspirin, Ibuprofen, Nitrofurantoin. (hemolysis IS D PAIN)

18

hematologic- megaloBLASTic anemia

Phenytoin, Methotrexate, Sulfa drugs (having a BLAST with PMS

19

hematologic- Thrombocytopenia

Heparin, Cimetidine

20

hematologic- Thrombotic complications

OCPs (i.e. estrogens)

21

musc/skin/connective tissue - fat redistribution

protease inhibitors, glucocorticoids

22

musc/skin/connective tissue - gingival hyperplasia

phenytoin, verapamil, cyclosporine, nifedipine

23

musc/skin/connective tissue -hyperuricemia (gout)

Pyrazinamide, Thiazides, furosemide, niacin, cyclosporine (painful Tophi and Feet Need Care)

24

musc/skin/connective tissue -hematologic- myopathy

fibrates, niacin, colchicine, hydroxychloroquine, interferon alpha, penicillamine, statins, glucocorticoids

25

musc/skin/connective tissue - osteoporosis

corticosteroids, heparin

26

musc/skin/connective tissue -photosensitivity

sulfonamides, amiodarone, tetracyclines (5-FU)

27

musc/skin/connective tissue - Rash (STEVENS-JOHNSON syndrome)

anti-epileptic drugs (ethosuximide, carbamzazepein, lamotrigine, phentoin, phenobarbital, Allopurinol, sulfa drugs, penicillin)

28

musc/skin/connective tissue -Sle like syndrome

Sulfa drugs, Hydralazine, INH, Procainamide, Phenytoin, Etanercept (having lupus is 'SHIPPE')

29

Neuro - Cinchonism

quinidine, quinine

30

Neuro -Parkinson like syndromes

Antipsychotics, Reserpine, Metoclopramide (cogwheel rigidity of the ARM)

31

Neuro -Seizures

INH (vit b6 deficiency), Bupropion, Imipenem/cilastatin, Tramadol, Enflurane, Metoclopramide (with seizures, I BITE My tongue)

32

Neuro -Tardive dyskinesia

antispychotics, metoclopramide

33

respiratory - pulmonary fibrosis

bleomycin, amiodarone, busulfan, methotrexate (breathingair badly from medications)

34

renal/genitourinary - diabetes insipidus

Lithium, demeclocycline

35

renal/genitourinary -Fanconi syndrome

Expired tetracycline

36

renal/genitourinary -hemorrhagic cystitis

cyclophosphamide, ifosfamide (prevent by coadministering with mesna)

37

renal/genitourinary -interstitial nephritis

methicillin, NSAIDS, furosemide

38

renal/genitourinary -SIADH

Carbamazepine, cyclophosphamide, SSRIs (Can't Concentrate Serum Sodium)

39

multiorgan - disulfiram like reaction

metronidazole, cephalosporins, griseofulvin, procarbazine, 1st generation sulfonylureas

40

multiorgan - nephrotoxicity ototoxicity

Aminglcosides, vanomycin, loop diuretics, cisplatin

41

CYP inducers

chronic alcohol use, Modafinil, St. John's wort, Phenytoin, Phenobarbital, Nevirapine, Rifampin, Griseofulvin, Carbamazepine

42

CYP inhibitors

acute alcohol abuse, gemfibrozil, ciprofloxacin, Isoniazid, Grapefruti Juice, Quinidine, Amiodarone, Ketoconazole, Macrolides, Sulfonamides, Cimetidine, Ritonavir

43

Sulfa drugs

Probenecid, Furosemide, Acetazolamide, Celecoxib, Thiazides, Sulfonamide antibiotics, Sulfasalazine, Sulfonylureas.

44

What are the non-depolarizing paralytics?

Atracurium or vecuronium

45

'prost'

Latanoprost