Drug therapy in pregnancy Flashcards Preview

D&T 4 exam 1 > Drug therapy in pregnancy > Flashcards

Flashcards in Drug therapy in pregnancy Deck (26):
1

Diethylstilbestrol was used for

prevention of premature birth, miscarriage and pregnancy problems

2

Diethylstilbestrol is bad because

clear cell adenocarcinoma of vaginia

3

what is Bendectin used for

nausea/vomiting during pregnancy
- withdrawn with no evidence

4

Thalidomide ? why was it withdrawen ? what is used for today

- control nausea/vomiting
- altered face/ear
- chemotherapy

5

what drugs do not pass to fetus

insulin and heparin

6

A

- studies failed to demonstrate a risk to the fetus in the first trimester of pregnancy
- (and there is no evidence of risk in later trimesters).

7

B

Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women

8

C

Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

9

D

There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

10

X

Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use of the drug in pregnant women clearly outweigh potential benefits.

11

treat bacterial vaginosis

metroidazole

12

treat vaginal candidiasis

topical azoles

13

treat UTI

penicillins

14

side effects of iron of folic acid

nausea and constipation

15

treat hyperthyroidism

carbimazole
propylthiouricil

16

diabetic drug

mefromin 2/3 trimester

17

treatment of pre-eclamptic

delivery
hydralazine, methyldopa, labetalol

18

pre-eclamptic what do you not used

Ace
Arb
nitroprusside

19

Phenytion

fetal hydantion sydnrome

20

carbamazepine

neural tube defect

21

valporic acid

neural tube dificits

22

asthma treatment

inhaled glucocorticouds first line
systemic
leukotrience inhibits -3

23

higher doses of Ondansetron

QT prolongation

24

hyperemesis gravidarium

severe nausea/vomiting

25

treatment of depression

Sertaline- safest
Paxil- cardiac defects

26

problem with tobacco abuse

premature labor, low birth weigh