Uterus, fallopian tubes Flashcards Preview

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Flashcards in Uterus, fallopian tubes Deck (54):
1

when does proliferative phase occur

end of menses till ovulation

2

what hormone is predominates the proliferative phase

estrogen

3

glandular mitosis occurs in what phase

proliferative phase

4

what does basal vacuolation mean

ovulation

5

histo for secretory phase

subnuclear vacuoles
tortuous glands

6

most common cause of dysfunctional uterine bleeding (DUB)

anovulatory cycle

7

why would anovulatory cycle cause dysfunctional uterine bleeding

prolonged estrogen without development of progesterone phase

8

what is inadequate luteal phase

corpus luteum does put out enough progesterone

9

how do you diagnose inadequate luteal phase

perform bx after ovulation

10

when is acute endometritis seen?

after delivery or miscarriage

11

what is seen in histo for acute endometritis

microabscesses
glandular epithelium

12

who can get chronic endometritis

chronic PID
postpartum/postabortion
intrauterine contraceptive devices
pts with TB

13

hist what is seen in chronic endometritis

plasma cells in endometrium

14

What is endometriosis

endometrial glands and stroma in abnormal locations outside the uterus

15

what are 3 theoreis for endometriosis

1. regurgitation theory: retrograde menses

2. metaplastic theory: may arise directly from coelemic

3. lymphvascular: spread through pelvic vessels

16

what is the gross image of endometriosis

little powder burn marks

17

histo for endometriosis

collection of endometrial glands and stroma

18

Endometriosis in ovary is also called what

chocolate cyst
endometrioma

19

what is endometrial polyps

polypoid mass occurs in endometrium

20

what are 2 types of endometrial polyps

1. contains functional endometrium
2. contains cystic, hyperplastic epithelium

21

hist for endometrial polup

multiple dilated endometrial glands

22

What is a cause of excessive uterine bleeding

endometrial hyperplasia

23

what causes endometrial hyperplasia

prolonged estrogen stimulation

24

What are 4 associated condition with endometrial hyperplasia

1. menoapuse
2. polycystic ovarian disease
3. excessive ovarian cortical function
4. prolonged estrogen replacement therapy

25

What gene is deleted in endometrial hyperplasia

PTEN

26

What happens when PTEN is inactivated

endometrial cells become more sensitive to stimulation to by estrogen

27

what type of endometrial hyperplasia has increased gland to stromal ratio and cyst formation

simple hyperplasia

28

what type of endometrial hyperplasia has increased glands with more crowding, enlargement and cytologic atypia

complex hyperplasia

29

what is atypical complex hyperplasia

cytologic atypia

30

how is complex hyperplasia treated

hysterectomy

31

histo for simple hyperplasia

increased number of simple dilated glands

32

histo for complex hyperplasia

infolding and complex gland

33

histo for atypical hyperplasia

increase glands and complex glands
- nuclear features

34

What is the most common invasive carcinoma of female genital tract

endometrial carcinoma

35

what are risk factors for endometrial carcinoma

- estrogen
- obesity
- nulliparous
- hypertension
- diabetes

36

what type of endometrial carcinoma has favorable prognosis

- prolonged estrogen stimulation

37

what is non associated excessive estrogen endometrial carcinoma resemble

adenocarcinoma in ovary
- papillary serous

38

gross appearance of endometrial carcinoma

thickened endometrium
polypoid mass

39

microscopic appearance of endometrial carcinoma

Adenocarcinoma : papillary serous

40

What happens in stage 1 endometrial carcinoma

confined to uterus

41

how might endometrial carcinoma present

asymptomatic
my see bleeding

42

what is leiomyomas? what else is it called

benign tumor
fibriods

43

gross appearance of leiomyomas

- well-circumscribed firm white masses

44

histo for leiomyomas

whorled bundles of bland muscle with low
-mitotic count

45

clinical symptoms for leiomyomas

asymptomatic
- associated with abnormal bleeding, urinary frequency, pain, impaired fertility

46

Leiomyosarcoms arises from what layer

myometrium

47

gross apperance of leiomyosarcoma

- bulky fleshy mass within wall
- poypoid mass
-

48

histo for leiomyosarcoma

- increased mitotic rate
- cytologic atypia

49

where can leiomyosarcoma spread

lung, bone, brain

50

Name a fallopian tube infection? what cuauses it?

- suppurative salpingitis
- gonococcus

51

what is a benign lesion of the fallopian tube

endometriosis

52

what are paratubal cysts

small to prominent cysts hanging off fallopian tubes

53

another name for paratubal cysts

hydatid cyst of morgagni

54

prognosis for fallopian tube adenocarcinoma

poor