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Flashcards in Thyroid - Denning Deck (71)
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1

What do parafollicular cells secrete

calcitonin

2

Graves disease

hyperthyroidism

3

define hyperthyroidism and thyrotoxicosis

hyperthyroidism: hyperfunction
thyrotoxicosis: leakage of thyroid hormone

4

what is struma ovarii

thyroid tissue in ovary

5

what does hyperthyroidism do to basal metabolic rate

increases

6

GI signs and symptoms for hyperthyroidism

hypermotility
absorption
diarrhea

7

Nervous system signs and symptoms for hyperthyroidism

overactive sympathetic
- wide gazing stare
- lid lag
-- Stimulation of levator palebrae superioris

8

what is thyroid storm

abrupt onset of thyrotoxicosis
medial emergency

9

clinical features of thyroid storm

tachycardia
thermoregulatory dysfunction ( high temp)
nausea, vomiting

10

when can thyroid storm be seen

in Grave's disease
following surgery

11

what are blood values for hyperthyroidsim

high T4
low TSH
- then measure t3

12

treatment options for hyperthyroidism

- beta-blockers
- thionamides - block new hormone synthesis
- prevent conversion of T4 to T3
-Radioiodine to ablate thyroid function

13

what are most cases of hypothyroidism

primary

14

what is endemic cretinism

mother is iodine deficient
baby becomes mentally retarded

15

myxedema

- generalized apathy and mental sluggishness
- applied to older child or adult

16

what other condition does myxedema mimmic

depression

17

what are symptoms for myxedema

cold intolerant
mucopolysaccharide-rich edema

18

what are TSH levels for primary and secondary hypothyroidism

primary: increased
secondary: decreased

19

what is the most common cause of endogenous hyperthyroidism

grave's disease

20

exophthalmos

bulging eyes

21

signs and symptoms for grave's disease

thyrotoxicosisi
exopthalmus
pretibial myxedema

22

what happens in grave's disease

autoantibodies
TSI - TSH receptor
TGI - TSH receptor
TBII - prevents binding of TSH

23

histo for Grave's disease

- may have papillae without fibrovascular core
- colloid scalloping

24

What organs does Grave's impact? how

Heart: hypertophied and ischemia
ophthalmology: mucopolysaccharides and lymphocytes
Dermopathy: Pretibial myxedema

25

how can you treat Grave's

- beta-blockers
- thionamides
- radioiodine ablation
- surgery

26

what is the most common thyroid disease

goiters

27

what are problems that arise from goiters

- cosmetic problems
- airway obstruction

28

what syndrome is seen with goiters

plummer's syndrome

29

what is plummer's syndrome

- hyperfunctioning nodule forms in long standing goiter
- hyperthyroidism
- no ophthalmopahty or dermopathy

30

goiters can mask or mimic what

neoplasms