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Pharmocology > Endocrine Part 4-Adrenal.ppt > Flashcards

Endocrine Part 4-Adrenal.ppt Flashcards

1
Q

Which are Glucocorticoids

a. prednisone
b. fludrocortisone
c. methylprednisolone
d. hydrocortisone

A

a. prednisone
c. methylprednisolone
d. hydrocortisone

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2
Q

Mineralocorticoids

a. prednisone
b. fludrocortisone
c. methylprednisolone
d. hydrocortisone

A

b. fludrocortisone

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3
Q

What is CORTICOSTEROIDS suffix ?

A

One

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4
Q

CORTICOSTEROIDS are secreted from?

a. Adrenal medulla
b. Adrenal cortex

A

b. Adrenal cortex

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5
Q

Aldosterone?

a. Glucocorticoids (?)
b. Mineralocorticoids (?)

A

b. Mineralocorticoids

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6
Q

Cortisol

a. Glucocorticoids (?)
b. Mineralocorticoids (?)

A

a. Glucocorticoids

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7
Q

Do CORTICOSTEROIDS deal with various sexual hormones?

Y/N

A

Yes

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8
Q

Cortisol level peak when?
a. Morning
b. Afternoon
C. Night time

A

a. Morning

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9
Q

Since cortisol natually peaks in the morning when should CORTICOSTEROIDS be given?
a. Morning
b. Afternoon
C. Night time

A

a. Morning

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10
Q

CORTICOSTEROIDS may inhibit or increase:

a. Metabolism
b. Inflammation
c. Both

A

c. Both

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11
Q

Which is true about Cortisol

a. Relieves stress
b. Stress hormone
c. Increases blood glucose during stress for survival
d. Decreases blood glucose during stress for survival
e. Fuel for brain

A

b. Stress hormone
c. Increases blood glucose during stress for survival
e. Fuel for brain

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12
Q

Which is true about Cortisol Metabolic Effects:

a. Gluconeogenesis- breakdown of proteins to amino acids
b. Hypertrophy is an increase and growth of muscle cells.
c. Lipolysis- increased free fatty acids
d. Decreased muscle mass,
e. Increased muscle mass,
f. Thinning of skin
g. Thicking of skin,
h. Hyperglycemia
i. Hypoglycemia
j. Moon face and buffalo hump
k. Decrease the breakdown of bone matrix (osteoporosis!)
m. Increase the breakdown of bone matrix (osteoporosis!)

A

a. Gluconeogenesis- breakdown of proteins to amino acids
c. Lipolysis- increased free fatty acids
d. Decreased muscle mass,
f. Thinning of skin
h. Hyperglycemia
j. Moon face and buffalo hump
m. Increase the breakdown of bone matrix (osteoporosis!)

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13
Q

Whats true about Cortisol Inflammation Effects:

a. It blocks Cyclo-oxygenase
b. It does’t block Cox 1 and Cox 2
c. It does block Cox 1 and Cox 2
d. It blocks prostaglandins similar to NSAIDS
e. It should be taken with food like NSAIDS
f. It Shouldn’t be taken with food like NSAIDS

A

a. It blocks Cyclo-oxygenase
c. It does block Cox 1 and Cox 2
d. It blocks prostaglandins similar to NSAIDS
e. It should be taken with food like NSAIDS

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14
Q 
Which is true about Mineralocorticoids- aldosterone
a. hypoglycemia
b. hyperglycemia
c. Hypercalcemia
d. Hypocalcemia
e. hypernatremia
f. hyponatremia
g. Sodium retention
H. hypokalemia
A

b. hyperglycemia
d. Hypocalcemia
e. hypernatremia
g. Sodium retention
H. hypokalemia

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15
Q

Which is a disease that needs CORTICOSTEROIDS

a. Reye syndrome
b. Addison’s Disease
c. Kawasaki disease

A

b. Addison’s Disease

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16
Q

Which is lab values of low Cortisol

a. Hypoglycemia
b. Fatigue
c. Hypotension
d. Anorexia
e. N/V/D
f. Constipation

A

a. Hypoglycemia
b. Fatigue
c. Hypotension
d. Anorexia
e. N/V/D

17
Q

Which are Glucocorticoids:

a. prednisone
b. fludrocortisone
c. methylprednisolone
d. hydrocortisone

A

a. prednisone
c. methylprednisolone
d. hydrocortisone

18
Q

Which are Mineralocorticoids:

A

b. fludrocortisone

19
Q

Which is LOW dose: physiologic effects?

a. prednisone
b. fludrocortisone
c. methylprednisolone
d. hydrocortisone
e. adrenal insufficiency
g. inflammation

A

a. prednisone
c. methylprednisolone
d. hydrocortisone
e. adrenal insufficiency

20
Q

Which is HIGH dose: pharmacologic effects

a. prednisone
b. fludrocortisone
c. methylprednisolone
d. hydrocortisone
e. adrenal insufficiency
g. inflammation

A

a. prednisone
c. methylprednisolone
d. hydrocortisone
g. inflammation

21
Q 
treat adrenal insufficiency
CHRONIC or ACUTE
a. prednisone
b. fludrocortisone
c. methylprednisolone
d. hydrocortisone
A

a. prednisone
c. methylprednisolone
d. hydrocortisoneA
CHRONIC

22
Q 
treat inflammation
CHRONIC or ACUTE
a. prednisone
b. fludrocortisone
c. methylprednisolone
d. hydrocortisone
A

a. prednisone
c. methylprednisolone
d. hydrocortisone
ACUTE

23
Q 
Which treat the following:
IBS, Crohns- GI Diseases
Asthma, COPD- Pulmonary
Poison Ivy, Rashes- Dermatology
a. prednisone
b. fludrocortisone
c. methylprednisolone
d. hydrocortisone
A

a. prednisone
c. methylprednisolone
d. hydrocortisone

24
Q 
Which treat the following:
Adrenal Insufficiency- Endocrinology
Rheumatoid Arthritis - Immunology
Leukemia/Lymphomas - Hematology
a. prednisone
b. fludrocortisone
c. methylprednisolone
d. hydrocortisone
A

a. prednisone
c. methylprednisolone
d. hydrocortisone

25
Q 
Which treat the following:
Joints- reduce inflammation
Cerebral Edema
Organ transplant (decrease immune response)
a. prednisone
b. fludrocortisone
c. methylprednisolone
d. hydrocortisone
A

a. prednisone
c. methylprednisolone
d. hydrocortisone

26
Q 
Which treat the following:
Spinal cord injury
Antiemetic
NEONATES- Lung development
a. prednisone
b. fludrocortisone
c. methylprednisolone
d. hydrocortisone
A

a. prednisone
c. methylprednisolone
d. hydrocortisone

27
Q 
Whiich treats
Addison’s Disease
a. prednisone
b. fludrocortisone
c. methylprednisolone
d. hydrocortisone
A

b. fludrocortisone

28
Q 
Which treats
Orthostatic Hypotension
a. prednisone
b. fludrocortisone
c. methylprednisolone
d. hydrocortisone
A

b. fludrocortisone

29
Q 
C -
U -
S -
H -
I -
N -
G -
O - 
I -
D -
A 
C –Cataracts
U –  Ulcers (peptic ulcer disease)
S –Skin thinning/Striae, Salt retention
H – Hypertension, Hirsutism
I – Immunosuppression, Infections
N – Necrosis of femoral heads]
G – Glucose elevation/Glaucoma
O – Osteoporosis, Obesity
I – Impaired wound healing
D ​– Depression/mood changes
30
Q

Cortostreids Adverse Effects

a. hypokalemia
b. hyperkalemia
c. hyponatremia + water
d. hypernatremia + water
e. Hyperglycemia
f. Hypoglycemia
g. hyperlipidemia ( Elevated Cholesterol
h. hypolipidemia ( Decreased Cholesterol
i. Elevated WBC - Not getting outside blood, Increased j. Infections
k. Decreased WBC - Not getting outside blood, m. Increased Infections

A

a. hypokalemia
d. hypernatremia + water
e. Hyperglycemia
g. hyperlipidemia ( Elevated Cholesterol
i. Elevated WBC - Not getting outside blood, Increased j. Infections

31
Q

Select what is true about Cortostreids
a. Take in the morning with food
b. Take in the afternoon without food
c. Patient are at risk for hyperglycemia, so check BG levels
d. Patient are at risk for hypoglycemia, so check BG levels
e. MUST TAPER (reduce dosage slowly) to prevent adrenal atrophy
f. Safe to with other people/crowds who may be SICK + LIVE VACCINES
g. AVOID other people/crowds who may be SICK
+ NO LIVE VACCINES

A

a. Take in the morning with food
c. Patient are at risk for hyperglycemia, so check BG levels
e. MUST TAPER (reduce dosage slowly) to prevent adrenal atrophyg. AVOID other people/crowds who may be SICK
+ NO LIVE VACCINES

32
Q 
Are the following: Cortosteriod
Abnormal hair growth
Thinning of the skin + Scarring
Cushing’s Disease - fatty hump between the shoulders
a. Short term effect
b. Longterm effect
A

b. Longterm

33
Q

Select what is true about Cortostreids

a. Children growth will remain normal
b. Children Growth may be delayed
c. Addison- do not need doses of steroids prior to stressful events
d. Addison- need doses of steroids prior to stressful events
e. Addison - Giving supplemental doses can prevent ADRENAL CRISIS
f. Addison - Giving supplemental doses can’t prevent ADRENAL CRISIS

A

b. Children Growth may be delayed
d. Addison- need doses of steroids prior to stressful events
e. Addison - Giving supplemental doses can prevent ADRENAL CRISIS

34
Q

Which are low dose therapy for cortostreriods

a. Topical
b. PO
c. IV
d. Intranasal sprays

A

a. Topical

d. Intranasal sprays

35
Q

Select what is true about Cortostreids

a. NSAIDS- can increase GI issues, peptic ulcer disease
b. NSAIDS- can decrease GI issues, peptic ulcer disease
c. Can be taken with Grape Juice
d. Can not be taken with Grape juice

A

a. NSAIDS- can increase GI issues, peptic ulcer disease

d. Can not be taken with Grape juice

36
Q

Addison High Stress what is true?

a. EXTRA doses of steroids
b. LESS doses of steroids
c. Failure to do so can result in SHOCK and DEATH
d. SUPPLEMENTAL/EXTRA Doses of Steroids for Addison’s Patients
e. SUPPLEMENTAL/LOW Doses of Steroids for Addison’s Patients
f. Addison’s patients are supposed to wear bracelets in the event of an accident

A

a. EXTRA doses of steroids
c. Failure to do so can result in SHOCK and DEATH
d. SUPPLEMENTAL/EXTRA Doses of Steroids for Addison’s Patients
f. Addison’s patients are supposed to wear bracelets in the event of an accident

Pharmocology (36 decks)

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