Flashcards in ENDOCRINE SYSTEM Deck (151)
What is a goitre?
Abnormal swelling of thyroid gland
What are the causes of goitre?
thyroid cancer (1 in20 of goitres)
Drugs: lithium and immunosuppressors
What can be a serious side effect of goitre?
Can compress trachea or esophagus
What is cushings syndrome?
When the body produces to much cortisol
What type of hormone is cortisol and what is its main aim?
It's the stress hormone and maintains homeostasis
What is cushings disease and how does it cause cushings syndrome?
It is hyperplasia and tumour growth on the pituitary gland causing excess production of ACTH which leads to excess production of cortisol
How does Corticotroponin releasing hormone from the hypothalamus cause Cushing's?
While rare it can cause excessive production of ACTH by the pituitrary gland
What does ACTH stand for?
What are non ACTH causes of cushings syndrome?
Adrenal adenoma and carcinoma
Long term corticosteroids use
What is the ratio of female to male in cushings?
What group of people have high incidence of cushings?
How long free does the urine have to be of cortisol to not have cushings?
What happens to your mood in cushings?
Depression and fatigue
What happens to your BP and glucose levels in cushings?
What is sub acute (de-quervain's) thyroiditis (self limiting)?
Self limiting painful goitre
Causes rise in erythrocyte sedimentation rate and no radio iodine uptake
What are the risk factors of hyperthyriodism?
High iodine uptake
Trauma and surgery to thyroid
Why does high uptake of iodine increase chance of hyperthyriodism?
Increases production of thyroxine
What are the physical signs and symptoms of hyperthyroidism?
What happens sexually in hyperthyroidism?
What heart related symptoms do you get in hyperthyroidism?
Palpitations (AF, SVT) and tremor
What rare signs and symptoms do you get in hyperthyroidism?
What drugs would you give to prevent thyroid production?
What are common side effects of hypothyriodism?
Hair loss in outer 1/3rd of eyebrow
How mentally does hypothyriodism effect a patient?
What heart complications can you get in hypothyriodism?
What is the treatment of hypothyriodism?
What drugs does Levothyroxine interact with?
What complication of hypothyriodism increases chance of CVD?
High cholesterol levels
What is the role of TSH and what organ is it released from?
It is released from the anterior pituitary gland and it controls the production of T3 and T4 from the thyroid gland