Flashcards in ENDOCRINE WORKSHOP Deck (33):
what does the endocrine system contain?
what are common endocrine disorders?
(Type 1, Type 2)
what is the gonadal function in females?
what is the gonadal function in males?
what is the Hypothalamic pituitary adrenal axis?
what is the Hypothalamic pituitary thyroid axis?
how is aldosterone secretion controlled?
independent of cortisol secretion
what hormones are involved in homeostasis?
Glucagon like peptide 1 (GLP-1)
what is insulin secreted by?
by pancreatic beta cells
what do beta cells sense?
what does insulin inhibit?
hepatic glucose release
NEFA release from adipose tissue
what does insulin down regulate?
what does insulin promote?
tissue glucose uptake
what is glucagon secreted by?
pancreas alpha cells
what is the secretion of glucagon negatively regulated by?
what is the secretion of glucagon positively regulated by?
what does glucagon promote?
glucose release (liver)
what does glucagon stimulate?
NEFA release adipose tissue
what is GLP-1 secreted by?
small intestine L cells
what is GLP-1 secretion promoted by?
what does GLP-1 act on?
beta cells -Promotes glucose mediated insulin secretion
what does GLP-1 inhibit?
what does GLP-1 delay?
does GLP-1 have a long or short half-life?
give examples of Catecholamines
what do Catecholamines include?
Hormones and neurotransmitters
what do Catecholamines promote?
glucose release from liver
what do Catecholamines stimulate?
what are the classifications of diabetes?
type 1 and type 2
what is type 1 diabetes?
rapid onset, life threatening. Autoimmunity
what is type 2 diabetes?
Metabolic, weight gain, excercise
Hypertension; dyslipidaemia; increase in CHD
what is the management of type 1 diabetes?