HOSPITAL ACQUIRED INFECTIONS Flashcards Preview

IMS > HOSPITAL ACQUIRED INFECTIONS > Flashcards

Flashcards in HOSPITAL ACQUIRED INFECTIONS Deck (23):
1

what is sterility?

an absolute state of total absence of viable micro-organisms

2

what is sterilisation?

where products are subjected to a process where all viable micro-organisms are either killed or removed. It is usually the last stage of production

3

give examples of natural non-specific defence mechanisms

unbroken skin
stomach acid
tears (contain antimicrobial enzyme)
Muco-Ciliary clearance from lungs

4

what are contaminants?

Bacterial spores
Fungal spores
fungi
gram +/-ve bacteria
viruses + prions

5

what needs to be sterile?

Parenteral products, injections (small volume), infusions (large volume)
Ophthalmic preparations especially if cornea is damaged
Products + devices applied to broken or burn damaged skin

6

give examples of things that need to be sterilised

Injections, infusions, eye drops+lotions, surgical instruments, dressings, some creams/ointments for burns/large open wounds

7

what are the 2 examples of a pyrogen test?

rabbit test
LAL test

8

what is bioburden?

total load of viable micro-organisms present in the product to be sterilised

9

how much does sterilisation reduce the bioburden by?

bioburden to 10-6 organisms per container

10

How long will the sterilisation process take?

Can work this out if you know the bioburden and the D-value of an organism resistant to the process

11

what is the D-value?

(for a thermal process) is the time taken at a fixed temp required to achieve a 90% reduction in the micro-organism population

12

what are the sources of contamination?

environment
people

13

how do UK hospitals try to improve hygiene?

Massive effort to educate staff and visitors
Compulsory staff handwashing training
Provision of alcohol gel / liquid
Clear signage / prompts

14

what are the hospital staffs responsibility to maintain hygiene?

Long fingernails + artificial nails banned
Remove jewellery at start of shift
Maintain good skin condition
must comply with local policies

15

what is the 'washing event'?

w

16

why was the surgical hand disinfectant proposed?

Traditional scrub methods now being re-evaulated
Alcohol handrubs and gels NOT
effective against Clostridium difficle spores

17

what is 'bare below the elbows'?

Aims to offer visual re-assurance to patients
may have hygiene benefit

18

how can you check and measure bioburden on surfaces?

Enzyme luciferase, from fireflies, reacts with an energy storage molecule (ATP) in cells to produce light.
Amount of light produced is proportional to the number of viable cells in the sample.

19

what is an ATP assay device?

Takes just 30 secs to perform test
Unit can store 100s of readings

20

what can be used to decontaminate a whole room?

hydrogen peroxide

21

what is a negative of using hydrogen peroxide to disinfect a room?

All patients + sensitive equipment must be moved out of ward,
hazardous fumes to contain, expensive

22

what is a positive of using hydrogen peroxide to disinfect a room?

Useful for serious outbreaks / contamination events.

23

what is now being tested to use to disinfect a whole room?

UV light