Flashcards in FA toxicology Deck (22)
name 4 mycotoxins
what fungi produces aflatoxins
what produces ergot toxin?
what does aflatoxins cause
dec appetite, reduced yeild and milk residues
what does ergot cause?
hyperthermia, reduced milk yeild, poor fertility and gangrene at extremities
what does ZON cause?
hyperthermia, gilts, hyper-oestrogenism, nymphomania, vulva swelling
what produces ZON and DON?
what does DON do?
reduces feed intake and milk production,
name 2 chemical types which block ACh-Esterases, cont nerve stimulation, discharge, XS salivation, paralysis
OPs and carbamates
treat with anti-cholinergic (atropine) and charcoal
when are nitrates at highest risk of causing disease?
after rain following dry spell, fertilisers (XS)
what doe nitrates do?
become nitrites which cause mHb (--> vasodil, anorexia, cyanosis, inc BP, HR, RR)
treat with methylene blue i.v
what dz and tx is seen for lead ingestion
dz = fasciculations, grinding, staggers, blind + dil pupils
tx = sedate (diaz), MgSO4, Ca++
what dz and tx is seen for copper ingestion?
dz = chronic intox in liver - haemolytic anaemia, jaundice, icterus, hepatomegaly
tx = shock IVFT or binding with molybdenum and sulfur
name 5 plants which are toxic to ruminants (and other spp)
4. tannins - oak
7. st johns wort
what dz does ragwort ingestion cause?
what dz does bracken cause?
BM depression - thrombocytopenia
what does yew cause?
what damage do tannins cause?
what animal is most at risk of rhododendrum toxicity which results in XS salivation, v++, staggers
what is another name for foxglove?
st johns wort has similar signs to another plant toxin, which one?
ragwort. both cause liver failure.