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Flashcards in Antimicrobial choice - EQ Deck (10):
1

What is the MoA of b-lactams?

MoA - interfere w cell wall
indication - gram +, anaerob
with aminog and FQs

2

cehalosporins?

MoA - resistant to bacterial defense.
indication - older gen like gram +, younger like gram -

3

aminoglycosides?

MoA - pumped into gram -, bind to 30s ribosome
indication - gram -, pseudomonas

4

chloramfenicol

MoA - binds to 50s ribosome
indication - broad spec, eye drops

5

pot. sulphonamides

MoA - inhibit folic acid, dec PABA
indication - broad spec.
NOT anaerobes
DONT give with detomidine = fatal dysrhythmia

6

tetracyclines

MoA - 30s ribosome, inhib protein synth
indication - broad spec. also protozoa, mycoplasma and erlichia

7

FQs

MoA - inhib DNA gyrase so DNA doesnt align
indication - broad spec.
NOT anaerobes.
excreted unchanged in urine

8

Macrolides

MoA - bind to 50S to inhibit protein synth
indication - ONLY to be given to foals with rhodococcus with rifampin

9

rifampin

MoA - inhib RNA polymerase, to decr synth
indication - rhodococcus, staph
stains everything red*

10

metronidazole

MoA - taken up by anaerobes, breaks into free rads which damage DNA
indication - ANAEROBIC and giardia*