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Flashcards in Female genital system Deck (50):
1

Bartholin cyst is

Posterior Lateral, unilateral, painful cystic lesion at the lower vestibule

2

Lichen sclerosis is characterized by

Thinning of the epidermis and fibrosis (sclerosis) of the dermis

White patchs with parchment-like vulvar skin

3

Lichen Sclerosis simply is

Atrophy and granuloma of vulva

4

Lichen simplex chronicus is characterized by

Hyperplasia of vulvar squamous epithelium

5

Lichen simplex chronicus presents as

Leukoplakia with thick, leathery vulvar skin

6

Extramammary Paget disease characterized by

Malignant epithelial cells in the epidermis of the vulva

7

Extramammary Paget disease presents as

Erythematous, pruritis, ulcerated vulvar skin

8

Paget cells are

PAS+

Keratin+

S100-

9

Melanoma is

PAS-

Keratin-

S100+

10

Adenosis of Vagina is

Focal persistence of columnar epithelium in the upper 1/3 of the vagina

11

What increases the risk of Adenosis

Exposure to DES in utero

12

Clear cell adenocarcinoma is

Malignant proliferation of glands with clear cytoplasm

Complication of DES-associated vaginal adenosis

13

Cancer from lower 2/3 of vagina goes into

Inguinal Node

14

Cancer from upper 1/3 of vagina goes to

Iliac Node

15

CIN 1 involves

Less than 1/3 of the thickness of the epithelium

16

CIN 2 involves

less than 2/3 of the thickness of the epithelium

17

CIN 3 involves

Slightly less than the entire thickness of epithelium 

Unlikely to reverse

18

Late complications of Cerivical carcinoma

Invade through the anterior uterine wall into the bladder blocking the ureter

19

High grade dysplasia in cervical carcinoma is characterized by cells with

Hyperchromatic (dark) nuclei and high nuclear to cytoplasmic ratios

20

Growth of the endometrium is driven by

Estrogen

(Proliferative phase)

21

Preparation of the endometrium for implantation is driven by

Progesteron

(secretory phase)

22

Asherman syndrome is a loss of

Basalis 

23

Endometrial Polyps arise as a side effect of

Tamoxifen

24

Endometriosis is

Endometrail glands and stroma ouside of the uterine endometrial lining

25

Location of endometeriosis

Ovary: chocolate cyst

Uterine ligament: pelvic pain

Pouch of Douglas: pain with defecation

26

Adenomyosis is

Endometeriosis that involves uterine myometrium

27

Psammoma bodies found in

Thyroid papillary

Meningioma

Papillary serous carcinoma (endometrium)

Mesothelioma

28

LH:FSH in PCOD

greater than 2 because you have a great increase in LH and decrease in FSH

29

Surface epithelial ovarian tumor marker

CA-125

30

Surface epithelial ovarian tumors derived from

Coelomic epithelium

31

What mutation increases risk of serous carcinoma of ovary and fallopian tube

BRCA1

32

Endometriod surface epithelial ovary tumors arise from

Endometriosis

33

Germ cell Ovarian tumor subtypes

  1. Teratoma (Fetal tissue)
  2. Embryonal carcinoma (Fetal tissue)
  3. Dysgerminoma (Oocytes)
  4. Endodermal sinus tumor (Yolk sac)
  5. Choriocarcinoma (Placental)

34

Struma ovarii is

A tertoma composed primary of Thyroid tissue

35

What is elevated in Dysgerminoma

Serum LDH

36

What is elevated in Endodermal sinus tumor (yolk sac tumor)

AFP

37

Schiller-Duval bodies are

Glomerulus-like strucutures seen in Endodermal Sinus tumor histology

38

What does choriocarcinoma look like

Small, hemorrhagic tumor with early hematogenous spread

39

What is raised in Choriocarcinoma

β-hCG

40

Reinke Crystals seen in

Sertoli-Leydig cell tumor

41

Meigs syndrome is

Fibroma, Pleural effusion, and Ascites

42

Pseudomyxoma peritonei is

Massive amounts of mucus in the peritoneum

43

Pseudomyxoma peritonei is due to

a mucinous tumor of appendix

44

Placenta previa (implantation of placenta in lower uterine segment) presents as

Third trimester bleeding

45

Placenta accreta is

Improper implantation of placenta into the myometrium

46

Cocaine as a teratogen causes

Intrauterine growth retardation

Placenta abruption

47

What teratogen causes limb defects

Thalidomide

48

What teratogen causes spontaneous abortions and hearing/visual impairment

Isotretinoin

49

HELLP is

Preeclampsia with thrombotic microangiopathy

50

HELLP stands for

Hemolysis

Elevated Liver enzymes

Low Platelets