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Flashcards in Gas Exchange Deck (16):
1

Requirement for gas exchange

Large, moist respiratory surfaces

2

Gills

Outfoldings of the body surface
Aquatic animals (fish, mollusks, crustaceans)
Effectiveness increased by ventilation and countercurrent flow of blood and water

3

Tracheal system

Tiny branches that penetrate the body
Insects
Air flow: trachea -> tracheole (branch of trachea) -> body cell
Can go from trachea to air sac (storage of air)

4

Air flow through mammalian respiratory system

Nostrils -> pharynx -> trachea -> bronchi (2 main branches of trachea into lungs- 1 branch per lung) -> bronchioles (branches of bronchi) -> alveoli
Alveoli: dead ends where gas exchange occurs

5

How a mammal breathes

Negative pressure breathing: lung volume increases as the rib muscles and diaphragm contract, pulling air in

6

Breathing control systems in humans

2 regions in brain: medulla oblongata and pons

7

Medulla oblongata

Regulation of rate and depth of breathing in response to pH changes in the cerebrospinal fluid and to match metabolic demands

8

Sensors in aorta and carotid arteries

Monitor O2 and CO2 concentrations in the blood
Exert secondary control over breathing

9

Diffusion of CO2 and O2

Diffuse from region of higher partial pressure to region of lower partial pressure

10

Respiratory pigments

Proteins that transport oxygen
Greatly increase the amount of oxygen that blood can carry

11

Hemoglobin

Respiratory pigment of almost all vertebrates
Contained in erythrocytes (red blood cells)

12

Cooperativity

Binding of O2 to one subunit of hemoglobin molecule induces the other subunits to bind O2 with more affinity

13

Loading and unloading of O2

1st oxygen molecule attaches to iron -> hemoglobin changes shape and can pick up each subsequent oxygen molecule more easily
Hemoglobin releases oxygen molecule -> strength of bond between iron and remaining oxygen molecules becomes progressively weaker

14

Dissociation curve for hemoglobin

Cooperative O2 binding and release
Hemoglobin retains less O2 at lower pH (higher CO2 concentration)- Bohr shift
x axis: partial pressure of O2
y axis: % O2 saturation of hemoglobin

15

CO2 transport in cells

CO2 produced by body tissues diffuses into interstitial fluid and plasma
Most of CO2 diffuses into red blood cells and is picked up and transported by hemoglobin
CO2 reacts with water in red blood cells, making H2CO3 (catalyzed by carbonic anhydrase)
H2CO3 dissociates into bicarbonate ion and hydrogen ion
Hemoglobin binds most of H+, preventing Bohr shift
Bicarbonate diffuses into plasma and is carried by bloodstream into lungs
Bicarbonate combines with H+, reforming H2CO3
CO2 formed from H2CO3 is unloaded from hemoglobin and diffuses into interstitial fluid
CO2 diffuses into alveolar space and is expelled during exhalation
Reduction of CO2 concentration in plasma drives breakdown of H2CO3 into CO2 and water in red blood cells

16

Diving mammal adaptations

High blood to body volume
Stockpile O2 and deplete it slowly
Can store large amounts of O2 in muscles in myoglobin proteins
Adaptations to conserve O2