Gastro-duodenal Disease Flashcards Preview

GI > Gastro-duodenal Disease > Flashcards

Flashcards in Gastro-duodenal Disease Deck (16):
1

What is dyspepsia?

Pain or discomfort in the upper abdomen

2

When should a patient with dyspepsia be referred for endoscopy?

Weight loss
Anaemia
Malaena/ Haematemesis
Dysphagia

3

What investigations should be done for dyspepsia?

Bloods
Drug history
Lifestyle

4

What is helicobacter pylori?

Gram negative, spiral shaped, flagellated bacteria

5

Where does helicobacter pylori colonise

Gastric type mucosa (does not penetrate further)

6

How are helicobacter pylori infections diagnosed?

Serology
Urea breath test
Stool antigen test
Biopsy

7

What is gastritis?

Inflammation in the gastric mucosa

8

What are the causes of peptic ulcers?

Helicobacter pylori infections
NSAIDS
Smoking

9

What are the clinical features of peptic ulcers?

Epigastric pain
Back pain
Nausea
Weight loss
Maleana/ Haematemesis if ulcers bleed

10

How are peptic ulcers treated?

Eradication therapy using proton pump inhibitors or H2R antagonists (H Pylori)
Stop NSAIDS and smoking

11

What is the eradication therapy for helicobacter pylori infections?

Triple therapy for 7 days (clarithromycin, amoxycillin, proton pump inhibitors)

12

What are the complications of peptic ulcers ?

Acute bleeding leading to malaena and haematemesis
Chronic bleeding leading to iron deficiency anaemia
Perforation
Fibrotic stricture

13

What is gastric outlet obstruction?

Consequence of any disease process that produces a mechanical impediment to gastric emptying

14

What are the symptoms of gastric outlet obstruction?

Vomiting
Early satiety
Abdominal distension
Weight loss
Metabolic alkalosis

15

What are the clinical signs of gastric outlet obstruction?

Low Cl, Na and K in bloods
Renal impairment

16

How is gastric outlet obstruction managed?

Endoscopic dilatation
Surgery