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Flashcards in Liver Symposium Deck (32):
1

What type of hepatitis cause enteric viruses?

Hepatitis A
Hepatitis E

2

What type of hepatitis cause parenteral viruses?

Hepatitis D
Hepatitis C
Hepatitis D

3

What type of hepatitis cause chronic disease?

Hepatitis B
Hepatitis C
Hepatitis D

4

How is hepatitis A transmitted?

Faecal-oral
Sexual
Blood

5

Who gets immunisation fro Hepatitis A?

Travellers
Occupational exposure
Chronic liver disease patients
Men who have sex with men (MSM)

6

How is hepatitis B transmitted?

Vertical (mother to child)
Sexual

7

What is the make up of the hepatitis B vaccine?

Only contains surface antigens

8

What are the drugs used to treat hepatitis C?

Sofobuvir
Ledipasvir

9

What type of virus is hepatitis D?

RNA
Resistant to treatment and usually coinfects with HBV

10

What is the treatment for hepatitis E?

No specific treatment or effective vaccine and is self limiting

11

What are the different types of fatty liver disease?

Non alcoholic steatosis
Non alcoholic steatohepatitis

12

What are the risk factors for fatty liver disease`?

Diabetes
Obesity
Hypertension
Hpercholesterolaemia
Age
Ethnicity (hispanic)

13

How do you diagnose fatty liver disease?

Biochemical tests (AST/ALT ratio)
Ultrasound
MRI/CT
Liver biopsy
Cytokeratin-18
Scoring system used

14

How do you treat fatty liver disease?

Diet and weight reduction
Exercise
Insulin sensitisers
Vitamin E
Weight reduction surgery

15

What is autoimmune hepatitis?

Elevated IgG

16

How is autoimmune hepatitis treated?

Long term azathioprine

17

What are the clinical signs of primary biliary cholangitis?

IgM elevated
Anti-mitochondrial antibody positive

18

What is the treatment for primary biliary cholangitis?

UDCA treatment

19

What are the clinical signs of primary sclerosing cholangitis?

pANCA positive
intra and extra hepatic bile ducts involvement
MRCP test

20

How do you treat primary sclerosing cholangitis?

Biliary stents

21

Who are the appropriate liver transplant candidates?

Hepatocellular carcinoma
Acute liver failure
Genetic diseases
Chronic liver disease with poor predicted survival and associated poor QOL

22

What are the contraindications for liver transplant?

Malignancy
Active and uncontrolled infection
Active substance or alcohol abuse
Severe cardiopulmonary or other comorbid conditions

23

What is the post operative liver transplant treatment?

ICU
Prophylactic antibiotics and anti fungal drugs
Anti rejection drugs (steroids, azathioprine, tacrolimus)

24

What dose CAGE stand for?

Cut down
Annoyed by criticism of your drinking
Guilty about your drinking
Eyeopener

25

What os the presentation of alcoholic hepatitis?

Jaundice
Encephalopathy
Infection is common
Decompensated hepatic function

26

What are the clinical signs of alcoholic hepatitis

Raised bilirubin
Raised GGT and AlkP
Alcohol history

27

What is the treatment for alcoholic hepatitis?

Treat infection and encephalopathy
Alcohol withdrawal
Protect against GI bleeding
Airway protection/ ITU care
Review nutrition (frequent feeds)
Thiamine

28

What is the presentation of spontaneous bacterial peritonitis?

Abdominal pain
Fever, rigors
Renal impairment
Sepsis
Tachycardia
Temp?

29

What are the clinical signs of spontaneous bacterial peritonitis?

Neutrophil count >0.25x10(9)/L
Protein <25g/L
Ascitic tap (cultures, WCC, fluid protein and glucose levels)

30

What is the treatment for spontaneous bacterial peritonitis?

IV antibiotics
Ascetic fluid drainage
IV albumin infusion

31

What are the causes of hepatic encephalopathy?

Infection
Drugs
Constipation
GI bleed

32

How do you treat hepatic encephalopathy?

Bowel clear out, lactulose, enemas
Antibiotics