Glandular fever (mononucleosis)

Question 1

What virus most commonly causes glandular fever (infectious mononucleosis)?

Answer 1

Epstein-Barr virus (EBV) – 80–90% of cases.

Question 2

How is EBV typically transmitted?

Answer 2

Via saliva – e.g., kissing or sharing utensils.

Question 3

What is the incubation period for EBV infection?

Answer 3

4–7 weeks.

Question 4

Does EBV lead to lifelong infection?

Answer 4

Yes, it establishes a lifelong latent infection (reactivates without always causing symptoms).

Question 5

Is EBV infection typically symptomatic in children?

Answer 5

No, it’s often asymptomatic in children.

Question 6

Name 3 serious complications of EBV infection.

Answer 6

Splenic rupture, airway obstruction, hepatitis.

Question 7

What is the classic triad of symptoms in glandular fever?

Answer 7

Fever, sore throat, and cervical lymphadenopathy.

Question 8

What is the mainstay of treatment for glandular fever?

Answer 8

Supportive care – rest, fluids, analgesia, antipyretics.

Question 9

Should antibiotics be prescribed for EBV?

Answer 9

No, unless there is a confirmed secondary bacterial infection.

Question 10

What should patients avoid for 3 weeks after onset of symptoms?

Answer 10

Contact sports or heavy lifting – due to risk of splenic rupture.