Flashcards in Haemopoiesis Deck (19):
What is the lifespan of neutrophils?
7 - 8 hours
What is the life span of a platelet?
7 - 10 days
What is the life span of a RBC?
Where do you usually find megakaryocytes?
What do megakaryocytes differentiate into?
What is the precursor cell for platelets?
What is a myelocytes?
An intermediate nucleated precursor cell between neutrophils and blast cells?
What is meant by a "blast cell"
A nucleated precursor cell
What embryological layer are haemopoetic stem cells derived from?
What is the first site of haemopoeisis in the embryo?
What three organs perform haemopoiesis in the fetus?
What is the most common site of bone marrow biopsy in an adult?
What is the name given to the interface between the bone marrow and the bone?
What are sinusoids in the bone?
Speciailised venules that form a reticular network of denestrated vessels. They regulat the passage os cell in and out of the circulation
What is meant by red bone marrow?
Haemopoitically actove marrow
What is meant by yellow bone marrow?
Fatty inactive marrow
What is meant by the myeloid erthyroid ratio?
relationship of neutrophils and precursors to proportion of nucleated red cell precursors (ranges from 1.5:1 to 3.3:1) – can change (eg reversal in haemolysis as a compensatory response)
What kind of cells does bone marrow aspirate look for?