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Haematology > Pancytopenia > Flashcards

Flashcards in Pancytopenia Deck (16):
1

Name 2 drugs can cause bone marrow failure?

Chloramphenicol
Chemotherapy drugs

2

What vitamin deficiencies can cause pancytopenia?

B12/folate deficiency

3

What virus can cause bone marrow failure?

HIV

4

List 5 causes of hypersplenism?

Portal hypertension
Congestive cardiac failure
Rheumatoid arthritis
Myelofibrosis

5

Name an inherited cause of bone marrow failure syndrome?

Fanconi's anaemia

6

What are the symptoms of anaemia?

Fatigue
SOB
Cardiovascular compromise

7

What are the symptoms of neutropenia?

Recurrent infections

8

What are the symptoms of thrombocytopenia?

Purpura
Petechiae

9

Will the marrow be hypocellular or hypercellular in aplastic anaemia?

Hypocellular

10

Will the marrow be hypocellular or hypercellular in myelodysplatic syndrome?

Hypercellual

11

Will the marrow be hypocellular or hypercellular in B12/folate deficiency?

Hypercellular. Problem with maturation

12

Will the marrow be hypocellular or hypercellular in hypersplenism?

Hypercellular

13

What are the options for supportive treatment in pancytopenia?

Red cell Transfusion
Platelet transfusion
Antibiotic prophylaxis (antibacterial) also antifungals and antivirals

14

How do you treat aplastic anaemia?

Immunosuppressive drugs

15

How do you treat congenital bone marrow failure?

Bone marrow transplant

16

How would you treat pancytopenia caused by HIV?

HAART to treat HIV which will correct the pancytopenia