Flashcards in Pancytopenia Deck (16):
1
Name 2 drugs can cause bone marrow failure?
Chloramphenicol
Chemotherapy drugs
2
What vitamin deficiencies can cause pancytopenia?
B12/folate deficiency
3
What virus can cause bone marrow failure?
HIV
4
List 5 causes of hypersplenism?
Portal hypertension
Congestive cardiac failure
Rheumatoid arthritis
Myelofibrosis
5
Name an inherited cause of bone marrow failure syndrome?
Fanconi's anaemia
6
What are the symptoms of anaemia?
Fatigue
SOB
Cardiovascular compromise
7
What are the symptoms of neutropenia?
Recurrent infections
8
What are the symptoms of thrombocytopenia?
Purpura
Petechiae
9
Will the marrow be hypocellular or hypercellular in aplastic anaemia?
Hypocellular
10
Will the marrow be hypocellular or hypercellular in myelodysplatic syndrome?
Hypercellual
11
Will the marrow be hypocellular or hypercellular in B12/folate deficiency?
Hypercellular. Problem with maturation
12
Will the marrow be hypocellular or hypercellular in hypersplenism?
Hypercellular
13
What are the options for supportive treatment in pancytopenia?
Red cell Transfusion
Platelet transfusion
Antibiotic prophylaxis (antibacterial) also antifungals and antivirals
14
How do you treat aplastic anaemia?
Immunosuppressive drugs
15
How do you treat congenital bone marrow failure?
Bone marrow transplant
16