Head and Neck 2 Flashcards Preview

Block 5 > Head and Neck 2 > Flashcards

Flashcards in Head and Neck 2 Deck (29):
1

singer's nodules

bilateral

2

vocal cord polyps

unilateral

3

reactive nodules

singer's nodules
polyps
smoker or singer

4

description of nodules

smooth, rounded
sessile or pedunculate
myxoid CT covered by squamous epithelium

5

squamous papilloma

benign neoplasm
soft, rasberry like
fingerlike projections
can occlude trachea

6

virus associated with squamous papillomas

HPV6, 11

7

risk factors for laryngeal carcinoma

cigarette smoking
alcohol

8

description of laryngeal cancer

ulcerating, fungating lesions

9

symptoms of laryngeal cancer

persistent hoarseness
dysphagia
dysphonia

10

branchial cysts

remnants of branchial arches or salivary inclusions in cervical nodes
circumscribed
lymphoid tissue inside
clear watery/mucinous with cellular debris
lateral

11

thyroglossal cyst

remnants of thyroid tract
lymphoid aggregates in walls
recur if not fully excised
medial

12

paragangliomas

neuroendocrine cell clusters associated with ANS
recur with incomplete resection

13

mutation associated with paragangliomas

MENII

14

mucocele

post traumatic blockage/rupture of salivary gland duct
swollen, blue

15

treatment of mucocele

excision

16

most common salivary gland lesion

mucocele

17

most common benign salivary gland tumor

pleomorphic adenoma

18

mutation in pleomorphic adenoma

PLAG1

19

pleomorphic adenoma

mesenchymal and epithelial cell components
painless, slow growing
low recurrence after excision
risk of malignant transformation increases overtime

20

carcinoma ex pleomorphic adenoma

epitheilal malignancy from pleomorphic adenoma

21

sarcoma

mesenchymal malignancy from pleomorphic adenoma

22

true malignant mixed tumor

epithelial and mesenchymal malignancy from pleomorphic adenoma

23

second most common benign salivary gland tumor

warthin tumor

24

warthin tumor

papillary structure with oncolytic cells surrounding lymphoid material
usually parotid gland

25

mutation associated with mucoepidermoid carcinoma

METC1-MAML2

26

most common malignant tumor of salivary glands

mucoepidermoid carcinoma

27

mucoepidermoid carcinoma

mixture of squamous, mucus secreting, intermediate cells
usually in parotid

28

adenoid cystic carcinoma

slow growing, recurrent
perineural invasion- grows up nerves
common dissemination
aggressive treatment required
cribriform pattern histologically

29

actinic cell carcinoma

looks like normal serous acing cells
usually in parotid
can metastasize to lymph nodes
good 5 year survival