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Flashcards in Hepatitis viruses Deck (32)
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1

all hepatitis viruses target ?

liver

2

all hepatitis viruses primarily infect and replicate where

hepatocytes

3

what is the family, genome, and virion of hepatitis A

family - picornoviridae
genome - (+) ssRNA
virion - nonenveloped

4

what routes of transmission can ALL hepatitis virus be spread

Sexual and parenteral (injection)

5

hepatitis A can be transmitted in what ways

sexual, parenteral, fecal-oral

6

what is the incubation period for HAV

15-40 (short)

7

what 2 hepatitis virus are known for having short incubation periods

hep A
hep E

8

which hepatitis viruses are known for having long incubation periods

hep B (60-180)
hep C (60-120)
hep D (60-180)

9

what is the family, genome, and virion of hepatitis B

family - hepadnaviridae
genome - circular dsDNA (unique)
virion - enveloped

10

what hepatitis virus has a DNA genome

hep B (circular dsDNA)

11

what hepatitis virus has a (-) ssRNA genome

hep D

12

how can hep B be transmitted

sexual, parenteral, vertical

13

what family of viruses must use reverse transcriptase ? why ?

hepadnaviridae
-b/c has an RNA intermediate

14

what hepatitis virus has the smallest genome of all human viruses

hep B

15

what hepatitis virus infection increases the risk of developing hepatocellular carcinoma (HCC)

hep B

16

what hepatitis has a vaccination and what is unique about this vaccine

hep B
-requires multiple innoculations

17

what hepatitis virus requires an activated HBV infection in order to replicate

hep D (rare in humans)

18

chronic hepatitis infections occur in what hepatitis viruses

hep B (5%)
hep C (80%)
hep D

19

what percentage of hepatitis B infections become chronic

5 %

20

what percentage of hepatitis C infections become chronic

80 %

21

what is the family, genome, and virion for hepatitis C infections

family - flaviviridae
genome - (+) ssRNA
virion - enveloped

22

what hepatitis virus can cause extrahepatic disease mixed cryoglobulinemia

HCV

23

what hepatitis viruses would you suggest interferon-alpha treatment ?

hep B
hep C
- reduces chances for chronic infections

24

what hepatitis viruses could exhibit long term sequelae

HBV
HCV
HDV

25

what hepatitis viruses are very rare in the US

HDV
HEV

26

what is the family, genome, and virion of Hep D

family - deltaviridae
genome - (-)ssRNA
virion - enveloped

27

what is the family, genome, and virion of Hep E

family - calciviridae
genome - (+)ssRNA
virion - nonenveloped

28

what hepatits virus has the highest percentage of individuals being seropositive in the US (have Ab to the virus)

Hep A

29

what hepatitis virus has the highest statistics of causing chronic liver disease death in the US

Hep C

30

what hepatitis virus has the most acute cases in the US

Hep B