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Flashcards in Neurological viruses Deck (28)
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1

what family of viruses are transmitted through arthropod vectors

togaviruses
flaviviruses

2

what are common resovoirs for diseases transmitted by arthropods

birds, small mammals

3

transmission requires _______ w/in the vector

replication

4

what is the family, genome, and virion for eastern equine encephalitis virus (EEE)

family - tagaviridae
genome - (+)ssRNA
virion - enveloped

5

of the 4 neurological viruses which has a genome of
(-)ssRNA

Rabies

6

what are the 4 neurological viruses ?

-eastern equine encephalitis (EEE)
-venezuelan equine encephalitis (VEE)
-west nile virus
-rabies virus

7

what is the family, genome, and virion of venezuelan equine encephalitis (VEE)

family - togaviridae
genome - (+)ssRNA
virion - enveloped

8

where does replication occur for EEE and VEE

cytoplasm of the host cell (RNA virus)

9

once EEE and VEE virus is introduced via the bite of an arthropod, the infected cells are distributed locally throughout the host via what cells

Langerhans cells

10

95 % of EEE and VEE virus cause what ?
the remaining 5 % causes ?

95% - viremia (rash and arthristis)
5% - encephalitis

11

How do you prevent and control the EEE and VEE viruses

live-attenuated TC-83 vaccine

12

are EEE and VEE prevalent in the US

Yes, eastern US cuz of migrating bird resovoirs

13

what is the incubation period for EEE and VEE ?

4-10 days

14

what is the incubation time of the west nile virus

2-14 days

15

for persons infected w/ west nile virus disease, what are the percentage breakdowns illnesses

80 % - asymptomatic infection
20 % - illness (fever/headache)
<1 % - neuroinvasive

16

How do you prevent and control west nile virus

-mosquito control strategies
-NO vaccine or treatment

17

is west nile virus prevalent in the US

Extremely common in US

18

what is the famile, genome, and virion of the rabies virus

family - rhabdoviridae
genome - (-)ssRNA
virion - enveloped

19

where does replication occur for the rabies virus

cytoplasm of the host cell

20

what neurological disorder frequently produces defective interferring particles

rabies virus

21

what is the incubation period of the rabies virus

1-3 months

22

what is the percentage of bites from a rabies resovoir that cause disease ?
what about if the bite is on the face/head ?

15 % cause disease
60 % if bit on face/head

23

what is the prevelance of rabies in the US

few cases, but very common in dogs in developing countries

24

how is the reabies virus spread and why does this make the incubation time variable

replicates locally untill finds neurons then passivley moves in axoplasm to the brain

25

what is the first symptoms of the rabies virus

hyrophobia - difficulty swallowing
cerebral dysfunction

26

what neurological disorder is almost always fatal

rabies virus

27

how do you prevent and control rabies virus

vaccine and post-exposure prophylaxis
-control by vaccinating dogs and domestic animals

28

how fast must you recieve treatment if you have been bitten by a rabies resovoir

4 days