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IHO Final > Immunology > Flashcards

Flashcards in Immunology Deck (17):
1

List components of innate immune system.

Physical barriers, phagocytes, complement, interferon

2

What type of macrophage is found in the liver?

Kupfer cells

3

What PAMP does the TLR3 PRR bind?

Viral double stranded RNA

4

What happens if the innate immune system is evaded?

get sick and/or acquired immune system takes over

5

Name the interferon released by infected cells?

IFN alpha and beta

6

Name a type of cytokine that attracts immune cells to inflamed tissue?

chemokine

7

All leukocytes are identified by this molecule?

cluster of differentiation (CD) 45

8

What cell initiates adaptive immunity?

phagocytes

9

Compare the response of the adaptive immune system from first time to second time exposure?

first exposure response takes 7-10 days
the second response faster and stronger

10

What is the difference between active and passive immunity?

active- exposure to antibody or vaccine
passive- immunoglobulin from mother to baby or transfusion

11

What are two ways that complement is activated?

pathogen -innate
antibody- adaptive

12

What two types of cells do B cells differentiate into?

plasma cells and memory B cells

13

What is unique about NKCs?

NKCs kill cells that do not have an MHCI complex on them

14

Where do mast cells reside?

skin, mucosa, conjunctiva, mouth, nose

15

What cytokine promotes diapedesis of PMNs?

IL-8

16

What receptors are found on mast cells?

Fc for IgE

17

What are the factors that promote differentiation of platelets?

GM-CSF, IL-3, IL-6 (colony stimulating factor)