Important Deck Test 2 Flashcards

(73 cards)

1
Q

major storage fuel

A

triglyceride

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2
Q

major circulating fuel

A

glucose

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3
Q

second major circulating fuel

A

triglyceride from lipoproteins

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4
Q

glycogen is stored where

A

liver, muscle

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5
Q

three major circulating fuels

A

glucose, triglycerides, fatty acids

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6
Q

three major storage fuels

A

triglycerides, proteins, glycogen

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7
Q

bonds in starch

A

alpha 1,4 ; alpha 1,6

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8
Q

amylose bonds

A

alpha 1,4 (linear)

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9
Q

amylopectin bonds

A

alpha 1,4 & 1,6 (branched)

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10
Q

triglyceride is made up of

A

glycerol, three fatty acids

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11
Q

gatty acid is conjugated to glycerol backbone via blank

A

ester bonds

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12
Q

which organ has highest ketogenic activity

A

liver

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13
Q

liver does not have this enzyme so it cannot use ketone bodies that i makes

A

3 ketoacyl coA transferase

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14
Q

second highest ketogenic organ

A

kidney

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15
Q

two fuels used by brain

A

ketones, glucose

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16
Q

organ with highest lipogenic activity

A

liver

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17
Q

organ with second highest lipogenic activity

A

adipose tissue

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18
Q

stage 1 metabolism takes macromolecules and turns them into monomers like blank from blank

A

aa, proteins

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19
Q

stage 1 metabolism

A

extracellular digestion polymers to monomers

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20
Q

stage 2 metabolism

A

acetyl coA production

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21
Q

stage 3 metabolism

A

produce atp

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22
Q

metabolic reactions can be regulated diferentially via

A
Substrate concentration
Cofactor concentration
Enzyme concentration
Enzyme modifications
Isozymes
Compartmentalization
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23
Q

aldose has more blank than ketose because it has one more stereocenter

A

stereoisomers

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24
Q

two carbons of glucose that join to form anomers

A

c1 aldehyde, c5 hydroxyl

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25
anomeric carbon of glucose
carbon 1
26
anomeric carbon of fructose
carbon 2
27
free anomeric carbon means it is a blank sugar
reducing
28
beta is more blank than alpha anomer
stable
29
lactose glycosidic bond
gal beta 1,4 g
30
sucrose glycosidic bond
g alpha 1,2 f
31
trehalose glycosidic bond
g alpha 1,1 g
32
raffinose glycosidic bond
gal alpha 1,6 g
33
raffinose requires blank for digestion
galactosidase
34
sucrose and trehalose are blank sugars
non reducing
35
pancreatic alpha amylase only cleaves these bonds in starch
g alpha 1,4 g
36
enzyme that digests dextrins
isomaltase (debrancher)
37
3 catalytic activities of sucrase isomaltase complex
maltose, sucrose, isomaltose
38
four glycosidases of brush border
glucoamylase, lactase, isomaltase, trehalase
39
secretin promotes release of blank
bicarbonate
40
cck promotes release of blank for carb digestion and blank for lipid digestion
pancreatic alpha amylase, bile salts
41
alpha amylase and glucoamylase both degrade starch by cleaving blank bonds
alpha 1,4 g
42
glucoamylase is a blank and cleaves from the blank end to liberate glucose while alpha amylase is a blank that cleaves blank
exoglucosidase, non reducing, endoglucosidase, internally
43
intestinal glucose/galactose absorption transporter
sglt 1
44
fructose absoprtion in intestine transporter
glut 5
45
glut 5 has passive absorption so it has a blank glycemic index than sglt 1
lower
46
factors that influence glycemic index
structure, enzyme, absorption mode
47
carbon of cholesterol ring that is ivolved in formation of an ester
3
48
enzymes involved in the formation of cholesterol esters
acat (intracellular), lcat (extracellular)
49
which cholesterol derivative is the precursor of vitamin d3
7 dehydrocholesterol
50
which organs generate vitamin d3 from 7 dehydrocholesterol
skin makes cholecalciferol, then liver and kidney make it active d3
51
which reaction is the rate limiting step in production of bile salts from cholesterol
7 alpha hydroxylase enzyme that converts cholesterol to 7a hydroxycholesterol, first step
52
two aa conjugated to bile salts
taurine, glycine
53
two amphibolic bile salt detergents related to taurine and glycine
chenocholic acid, cholic acid
54
pancreatic lipase works where
digestive tract
55
LPL works where
blood stream
56
lipoprotein lipase forms these
glycerol, fatty acids
57
pancreatic lipase forms these
2 monoglycerides, 2 fatty acids
58
fatty acids can be converted back to triglycerides via blank
fatty acyl transferase
59
pancreatic lipase requires blank
colipase
60
LPL requires blank for activation
ApoCII
61
LPL substrate is triglycerides from blank
chylomicrons
62
pancreatic lipase substrate
dietary triglycerides
63
nascent chylomicrons are blank
lipoproteins
64
nascent chylomicrons become mature when they accept these from HDL
apoC2/apoE
65
chylomicron remnants are created when blank digest them and remove their triglycerides
LPL
66
ApoC2 and ApoE are critical for digestion of blank
chylomicrons
67
largest lipoprotein
chylomicron (low density)
68
which lipoprotein has highest triglycerides
chylomicron
69
which liprotein has most proteins
HDL (high density)
70
HDL or LDL has more cholesterol?
LDL
71
functions of HDL
donate apoc2/apoe, extract cholesterol, converts cholesterol to cholesterol ester
72
cause of hypercholesterolemia
LDL receptor probs, LPL probs
73
steatorrhea is due to incomplete blank digestion
lipid