Lec 18 Fatty Acid Oxidation

Question 1

extracellular fatty acid carrier

Answer 1

serum albumin

Question 2

intracellular fatty acid carrier

Answer 2

fatty acid binding protein

Question 3

double bond in fatty acid is in this configuration

Answer 3

cis

Question 4

more saturated means blank melting point

Answer 4

high

Question 5

pufa keeps the membrane blank at low temps… so its like antifreeze

Answer 5

more fluid

Question 6

sodium hydroxide heating of pure lard creates blank

Answer 6

soap

Question 7

fatty acid activation requires blank atp

Answer 7

2

Question 8

glucose activation requires blank atp

Answer 8

1

Question 9

extracellular pyrophosphate (PPi) is a blank of tooth and bone formation

Answer 9

inhibitor

Question 10

biphosphonate is used to treat blank by inhibiting extracellular pyrophosphate (PPi)

Answer 10

osteoporosis

Question 11

Fatty acid activation occurs in the blank via blank and fatty acyl coA becomes fatty acyl carnitine…. only applies to blank fatty acids

Answer 11

cytosol, cat 1, long chain fatty acids C>12

Question 12

malonyl CoA is most abundant in the blank state and inhibits blank

Answer 12

fed, cat1

Question 13

carnitine helps burn blank more efficiently

Answer 13

fatty acids

Question 14

carnitine can be used to treat chronic blank

Answer 14

fatigue

Question 15

fatty acid oxidation steps are similar to last 3 steps of blank cycle

Answer 15

tca

Question 16

mcad oxidezes these

Answer 16

medium chain fatty acids (4-12 carbons)

Question 17

mcad deficiency causes blank

Answer 17

sids, hypoglycemia, decreased fatty acid oxidation

Question 18

total net yield of 1 palmitate (even chain) is

Answer 18

129 atp

Question 19

abc system of carboxylase that is required for carboxylation

Answer 19

atp, biotin, carbon

Question 20

methylmalonic acidosis is due to a deficiency of blank

Answer 20

vitamin b12

Question 21

stearate C18 net atp production

Answer 21

146

Question 22

oleate C18:1 net yield

Answer 22

144 (2 atp less because of double bond)

Question 23

peroxisomal fatty acid beta oxidation is for blank

Answer 23

very long and long chain fatty acids

Question 24

peroxisomes produce blank but mitochondria dont

Answer 24

hydrogen peroxide

Question 25

hydrogen peroxide is neutralized via blank

Answer 25

catalase

Question 26

high ldl and low hdl is blank

Answer 26

dyslipidemia