Infectious neurogical disease of the upper brain in cattle Flashcards Preview

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Flashcards in Infectious neurogical disease of the upper brain in cattle Deck (46)
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31

In the case of a botulism outbreak, whaat do you need to do?

type the botulism, get antisera

32

What does botulism look like?

hypokalemia

33

When can hypokalemia occur in cattle?

When farmers give corticosteroids after calving to prevent nervous ketosis. But also mimics aldosterone (mineralocorticoids) and kidneys retain sodium and get rid of potassium

34

Why might a vet get called out for lightening strike?

because may be covered under insurance. very hard to diagnose. only thing you can do is look on head or back through hide may find a burn mark or may find a burn mark at the bottom of when of the legs--grounded
Can also skin hide off--hemorrhagic area

35

Why can you get cattle electrocution?

wonky wiring, stray voltage

36

What are signs of heritable disorders in cattle?

typically born normal with onset of clinical signs at a specific age

37

What is BSE?

progressive death of braincells in cattle

38

What is a prion disease?

a group of related diseases (TSEs) characterized by specific damage t the brain
long incubation period

39

What are examples of prion disease?

1. scrapie--sheep
2. CWD--elk, deer
3. TME--mink
4. CJD--humans (creutzfeld jacob dz--multiple diseases)

40

What are types of creutzfeld jacob diz?

1 random--older people
2. inherited (FFI, GSS)
3. Kuru--papua new guinea

41

What are prions?

proteinaceous unfectious particle
natural uninfectious prion protein found in cells of normal animals
infectious prion folded in abnormal shape
change in shape makes it very stable

42

What is the pathogenesis of prion dz?

makes its way to brain
the infectious prion slowly changes normal prion into infectious prion. they bind together to form microscopic fibers

43

How do you diagnose BSE?

histopathology
electron microscopy
monoclonal antibody most common
break down the brain and have all protein break down and then look for prion (survives process)--faster

44

What do you need for diagnosis?

back of foramen magnum

45

What does BSE look like?

three key groups of signs
1. nervousness
2. aggression
3. problems walking (eventually become
downers)
excessive muzzle licking
don't like steps or doorways

46

Nearly all cases of BSE have been seen in what animals?

dairy