Neonatal diarrheas (swine) Flashcards Preview

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Flashcards in Neonatal diarrheas (swine) Deck (46)
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1

What are the two causes of neonatal diarrheas?

1. colibacillosis (ETEC)
2. transmissible gastroenteritis virus (TGE)

2

What are the two causes of neonatal diarrheas?

1. colibacillosis (ETEC)
2. transmissible gastroenteritis virus (TGE)

3

What age of animals get neionatal colibacillosis?

4

What is the source of ETEC?

environment, feces skin

5

What provides a protective immunity against ETEC for piglets

pre-farrowing vaccination

6

What is a risk factor for ETEC?

litters of young sows due to lower IgA in milk

7

What is the pathogenesis of ETEC?

1. adherence to small intestinal mucosa by fimbriae (F4, F5, F6, F41)
2. colonization
3. production of enterotoxins (STa, STb, LT)
4. secretory diarrhea

8

What are the clinical signs of ETEC?

1. diarrhea, dehydration, lethargy,d eath
2. peracute--death before dehydration
3. single or multiple piglets in litter affected

9

What does severity of ETEC depend on?

1. virulence
2. vaccination status of damn
3. environmental factors

10

How can cold cause a vicious cycle with ETEC?

Piglets have little brown fat, chill quickly (diarrhea, not eating)
Slows down GI tract and e. coli stay and propagate and secrete

11

What is the trend with litters affected and ETEC?

tends to have high prevalence within a litter but not necessarily between litters

12

What is seen on pathology ith ETEC?

1. dehydration
2. dilated, fluid filled smal intesteine
3. congestion of SI vasculature
4. dilated stommach--may contain undigested curd

13

What piglets should be submitted to diagnose ETEC?

1. acute

14

What piglets should be submitted to diagnose ETEC?

1. acute

15

What age of animals get neionatal colibacillosis?

16

What is the source of ETEC?

environment, feces skin

17

What provides a protective immunity against ETEC for piglets

pre-farrowing vaccination

18

What is a risk factor for ETEC?

litters of young sows due to lower IgA in milk

19

What is the pathogenesis of ETEC?

1. adherence to small intestinal mucosa by fimbriae (F4, F5, F6, F41)
2. colonization
3. production of enterotoxins (STa, STb, LT)
4. secretory diarrhea

20

What are the clinical signs of ETEC?

1. diarrhea, dehydration, lethargy,d eath
2. peracute--death before dehydration
3. single or multiple piglets in litter affected

21

What two types of TGE infections can occur?

epizootic infection (naive herd) enzootic infection (endemic)

22

How can cold cause a vicious cycle with ETEC?

Piglets have little brown fat, chill quickly (diarrhea, not eating)
Slows down GI tract and e. coli stay and propagate and secrete

23

What is the trend with litters affected and ETEC?

tends to have high prevalence within a litter but not necessarily between litters

24

What is seen on pathology ith ETEC?

1. dehydration
2. dilated, fluid filled smal intesteine
3. congestion of SI vasculature
4. dilated stommach--may contain undigested curd

25

How is dx of ETECC done?

1. history--age of onset, gilt liters
2. alkaline (secretory diarrhea)
3. gut loop--culture and sensitivity
4. histopathology--minimal villus atrophy
5. PCR--fimbriae, enterotoxin genes

26

What piglets should be submitted to diagnose ETEC?

1. acute

27

How is ETEC prevented/controlled?

1. prevent chilling
2. sanitation and hygiene
3. stop fostering
4. commercial killed bacterns (F4, F5, F6, F4, Sta, Stb, LT)
5. autogenous bacterins--farm specific
6. prevent dehydration (electrolytes)--not too much
7. antimicrobial

28

How do you get an autogenous vaccine for ETEC?

submit rectal swabs
submit e. coli isolated
test virulence
prepare vaccine

29

what antimicrobials should be used for ETEC?

1. parenteral
ceftiofur, TMS
NOT penicillin

30

Is TGEV reportable?

yes, provincially