Intro to Cancer Chemo: Control Anemia, Leukopenia, Thrombocytopenia

Question 1

Erythropoietin Mechanism

Answer 1

Stimulates RBC Production

Question 2

Erythropoietin Usefulness

Answer 2

Anemia

Question 3

Erythropoietin Side Effects

Answer 3

HTN

Thrombosis

Question 4

Darbepoetin Alfa Mechanism

Answer 4

Stimulate RBC Production

Question 5

Darbepoetin Alfa Usefulnes

Answer 5

Anemia

Question 6

Darbepoietin Alfa Side Effects

Answer 6

HTN

Thrombosis

Question 7

Filgrastim Mechanism

Answer 7

G-CSF: stimulate proliferation of neutrophil precursors

Question 8

Filgastim Use

Answer 8

Treat Leukopenia

Question 9

Filgastrim Side Effects

Answer 9

Bone Pain
Splenomegaly
Leukocytosis

Question 10

Sargramostim Mechanism

Answer 10

GM-CSF: stimulate proliferation/differentiation of hematopoietic progenitor cells

Question 11

Sargramostim Use

Answer 11

Treat Leukopenia

Question 12

Sargramostim Side Effects

Answer 12

Bone Pain
Myalgia
Fluid Retention
Capillary Leak Action

Question 13

Romiplostim Mechanism

Answer 13

TPO-Analog: stimulate platelet formation

Question 14

Romiplostim Use

Answer 14

Treat Thrombocytopenia

Question 15

Romiplostim Side Effects

Answer 15

N/V
Edema
Heart Failure
Arrhytmia
TPO: dizzy, abd pain, myalgia, insomnia

Question 16

Eltrombopag Mechanism

Answer 16

TPO-R agonist stimulate platelet formation

Question 17

Eltrombopag Use

Answer 17

Treat Thrombocytopenia

Question 18

Eltrombopag Side effects

Answer 18

N/V
Edema
Heart Failure
Arrhythmia