Flashcards in Intro to inflammation Deck (15)
Is inflammation part of the innate or delayed immune response?
What are some of the beneficial effects of inflammation?
Delivery of immune cells and proteins
Dilution of toxins
Eliminate substance & allow tissue repair
Stimulate further response
Entry of drugs
Excessive inflammation - Arthritis, syphyillis, lyme
During inflammation, what can vascular changes such as vasodilation result in?
During inflammation, what can vascular changes such as increased permeability result in?
Inc exudate (fluid and proteins)
Inc emigration of inflamm cells
What immune cells will do phagocytosis in inflammatioin?
What are the causes of chronic inflammation?
Persisting foreign bodies
Prolonged toxin exposure
What are some of the microscopic features of chronic inflammation?
New leukocytes (lymphocytes and macrophages)
Attempts at healing
Involves adaptive immunity
When can leukocytosis occur? (inc in leukocytes)
In acute and chronic inflammation
What are some patterns of inflammation?
Serous & Fibrinous
Suppurative - pus forming (purulent exudate)
What is granulomatous inflammation and what can cause it? Does it occur in chronic or acute iflamm or both?
Granulomas = collections of macrophages
Mycobacteria, especially tuberculosis
Chronic and acute
What are ulcers, give examples? Does it occur in chronic or acute iflamm or both?
Break in epithelial surface
Acute or chronic
In serous and fibrinous inflam, which is acute and which is chronic? e.g.blister
Serous - acute
Fibrinous - chronic
What immune cells are present in purulent exudate (supprative)?
What are the macro and microscopic features of crohn's disease?
Can affect anywhere
Bowel thickened, ulcers & fissures
Patchy, skip lesions
Chronic inflammatory cells predominate