Flashcards in IVF and Diuretics Deck (13):
how many mg/meq?
What is the equation for serum osms? What is a normal value?
what is D5W? What happens upon infusion? how much makes it to plasma?
5% dextrose. Osm of 278. Sugar metabolized, leaves only water. Less than 10% ends up in plasma
What is normal saline? How much ends up in plasma?
.9% Nacl. Osm of 308. 25% in plasma.
what is HNS? How much ends up in plasma?
.45% NaCl. ~167 cc in plasma
contains Na, Cl, K, Ca, lactate. Roughly same distribution as NS
What are the usually daily water needs?
100cc/kg for first 10 kg, 50 for next 10 kg, 20 for every kg over 20. 70 Kg=2500
who would you give NS to?
PT diuretic. Inhibits Carbonic anhydrase so less Na absorption and H+ secretion. good for met alkalosis
Furosemide torsemide, bumetanide. Inhibit Na/K/Cl symporter in TAL. Also cause Ca and K loss
HCTZ, chlorthalidone. Inhibit Na/Cl symporter in DCT. Less intracell Na leads to more favorable Na/Ca exchange and hyper calcemia
Why do thiazides and others cause hypokalemia?
^ Na to distal tubule where it is exchanged for K+