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Flashcards in IVF and Diuretics Deck (13):
1

how many mg/meq?

23

2

What is the equation for serum osms? What is a normal value?

2*Na+BUN/2.8+glucose/18. 285-295

3

what is D5W? What happens upon infusion? how much makes it to plasma?

5% dextrose. Osm of 278. Sugar metabolized, leaves only water. Less than 10% ends up in plasma

4

What is normal saline? How much ends up in plasma?

.9% Nacl. Osm of 308. 25% in plasma.

5

what is HNS? How much ends up in plasma?

.45% NaCl. ~167 cc in plasma

6

Lactated Ringers

contains Na, Cl, K, Ca, lactate. Roughly same distribution as NS

7

What are the usually daily water needs?

100cc/kg for first 10 kg, 50 for next 10 kg, 20 for every kg over 20. 70 Kg=2500

8

who would you give NS to?

volume deplete

9

acetazolamide

PT diuretic. Inhibits Carbonic anhydrase so less Na absorption and H+ secretion. good for met alkalosis

10

Loop diuretics

Furosemide torsemide, bumetanide. Inhibit Na/K/Cl symporter in TAL. Also cause Ca and K loss

11

Thiazides

HCTZ, chlorthalidone. Inhibit Na/Cl symporter in DCT. Less intracell Na leads to more favorable Na/Ca exchange and hyper calcemia

12

Why do thiazides and others cause hypokalemia?

^ Na to distal tubule where it is exchanged for K+

13

K sparing diuretics

Spironolactone, amiloride. Spironolactone blocks aldosterone which means fewer Na channels. Amiloride blocks Na channels directly. Can cause hyperkalemia