Kidney Pathology

Question 1

What stain might you use to view the renal basement membrane under light microscopy?

Answer 1

• Masson silver

Question 2

How does minimal change renal disease present? Who tends to get it? What does it look like on biopsy?

Answer 2

• Nephrotic syndrome
• Children
• Not much. Effaced podocytes

Question 3

How does IgA nephropathy present? What does it look like on biopsy?

Answer 3

• Nephritic syndrome
• Hypercellular glomeruli with interstitial fibrosis and inflammation. Crescentic glomerulonephritis

Question 4

If you have adult polycystic kidney disease, where else are you likely to have cysts?

Answer 4

• Liver
• Brain (Berry aneurysms)

Question 5

What does diabetic kidney disease look like on biopsy?

Answer 5

• Glomerulosclerosis

Question 6

What is the most common kind of renal-cell carcinoma? What are the complications of it?

Answer 6

• Clear-cell carcinoma
• Can metastasise to blood vessels (especially IVC spread), skin and breast