Lecture 15: Digestive system one Flashcards

1
Q

what does GI stand for?

A

Gastrointestinal tract

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2
Q

How long is the GI tract?

A

Hollow tube that is 30 feet long

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3
Q

what is the Gi tract composed of?

A
mouth
pharynx
oesophagus
stomach
small intestines 
large intestines(colon)
anus
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4
Q

what are the accessory organs to the GI tract?

A

teeth, tongue, salivary glands, liver, gallbladder, pancreas

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5
Q

what are the 3 main functions of the GI tract?

A

transportation, digestion, and absorption of food

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6
Q

what are the 6 main processes of the digestive system?

A
ingestion 
propulsion (motility)
mechanical digestion 
chemical digestion 
absorption 
defecation
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7
Q

what is ingestion and where does it happen?

A

intake of food done by the mouth

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8
Q

what is population where does it take place?

A

moving food along the digestion tract, involves the entire tract

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9
Q

what plays a role in swallowing?

A

oropharynx

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10
Q

what is mechanical digestion and which parts of the GI tract are involved?

A

breaking food down to its simplest form, chewing from teeth in the mouth, churning of the stomach, segmentation in the small intestine

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11
Q

what is chemical digestion and which parts of the GI tract are involved?

A

when enzymes break down food, in the mouth there’s salivary amylase, the liver has bile, also happens in the pancreas and stomach

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12
Q

what happens during absorption?

A

nutrients absorbed via lymph vessels and blood vessels.

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13
Q

what is Peristalsis?

A

movement of food going forwards due to the GI tract wall containing muscles which contract.

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14
Q

what is segmentation and where does it usually take place?

A

The mixing of food via the muscles in the wall of the GI tract alternating contractions between intestinal segments. This takes place in the small intestines.

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15
Q

how many layers does the wall of the GI tract have?

A

4

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16
Q

what are the layers of the wall of the GI tract called?

A

mucosa
submucosa
musculares externa
serosa

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17
Q

whats the functions of the mucosa?

A

secretes muscus, digestive enzymes
immune response
creates folds

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18
Q

what is the mucosa made of?

A

surface epithelium
lamina propria
Muscularis mucosae

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19
Q

what does the mucosa line?

A

Lines the lumen, separates GI lumen from internal environment

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20
Q

what does the surface epithelium of the mucosa contain?

A

Simple columnar epithelium and mucus-secreting goblet cells. Enzyme -secreting cells and Hormone-secreting cells

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21
Q

what does the lamina propria of the mucosa contain?

A

connective tissue: Small blood vessels and lymphatic vessels; Nerves; Lymphoid tissues: Lymph nodules and Peyer’s patches

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22
Q

what is the Muscularis mucosae?

A

thin smooth muscle

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23
Q

what is the submucosa?

A

Thick layer of connective tissue that is dense and has

elasticity

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24
Q

what does the submucosa contain?

A

large blood vessels
Lymphatic vessels
nerves branching into the mucosa and muscularis mucosae
Submucosal plexus -part of enteric nervous system

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25
what is the Muscularis externa responsible for?
for the motility of GI tract
26
what are the Two separate layers of smooth muscle that form the Muscularis externa?
Inner layer of circular muscle | Outer layer of longitudinal muscle
27
what NS is myenteric plexus apart of?
enteric nervous system
28
what does the myenteric plexus control?
GI tract motility
29
what is the Outermost Layer of GI wall?
serosa
30
How many layers does the serosa have?
2
31
what are the layers of the serosa ?
Inner layer of connective tissue | Outer layer is mesothelium
32
what is the serosa attached too?
the mesentery
33
what does the mesentery do?
maintains position of organs in the GI tract but also allows the to move
34
what's the function of the serosa?
protective layer
35
what part of food is chemically broken down so it can be digested?
carbohydrates, lipids and poteins
36
what are carbohydrates?
polysaccharides
37
what enzyme breaks down polysaccharides?
amylase
38
what breaks down disacharides?
maltase
39
what happens to monosaccharides ?
absorbed by specialised cells in the SI
40
what are the two types of amylase?
salivary amylase and pancreatic amylase
41
where is pancreatic amylase used?
small intentine
42
name 3 types of disaccharides?
lactose, maltose, sucrose
43
name three monosaccharides?
galactose, glucose and fructose
44
what breaks down triglycerides?
lipase
45
what does triglyceride break down into ?
monosaccharides and fatty acids
46
what produces lipase?
pancreases produces pancreatic lipase
47
what has to happen before pancreatic lipase can break down the fats?
the fats need to be emulsified by the bile salts from the liver
48
what enzymes can break down protein into peptides?
pepsin trypsin chymotrypsin
49
what enzymes break peptides down into amino acids?
aminopeptidase and carboxypeptidase
50
where is pepsin produced and whats its site of action ?
produced and used in the stomach
51
what are the pancreatic enzymes?
trypsin, chymotrypsin, | carboxypeptidase
52
what do accessory glands do?
secrete products into the lumen of the GI tract
53
what do salivary glands, liver and the pancreas secrete?
saliva bile pancreatic juice
54
what are the three salivary glands?
parotid gland sublingual gland submandibular gland
55
what is saliva comprised of?
99.5% water and 0.5% solutes
56
what enzymes are in saliva?
salivary a amylase salivary lipase lysozyme
57
what components are in saliva?
sodium, potassium chloride phosphate bicarbonate and mucus
58
whats it called when you have low production of saliva?
Xerostomia
59
what are the key components of bile?
bile salts, bile pigments, cholesterol
60
what is bile secreted from?
hepatocytes
61
what synthesize bile?
liver
62
where is bile stored?
gallbladder
63
what does the common bile duct do?
transports bile from liver/gallbladder to the duodenum
64
what is the ampulla of vatar?
when the common bile duct joins the pancreatic duct
65
what does the sphincter of oddi do?
regulates flow from the pancreas and gallbladder to the duodenum
66
what do exocrine glands of the pancreas produce?
pancreatic juice
67
what is the endocrine portion of the pancreas known as and what des it do?
Islets of Langerhans | secretes hormones
68
what does pancreatic juice neutralise?
neutralisesacidic chyme as it enters the duodenum
69
what enzymes does pancreatic juice contain ?
pancreatic amylase pancreatic lipase proteases:trypsin chymotrypsin, carboxypeptidase nucleases
70
what does the pancreatic acinar cell do?
synthesizes, stores, and secretes digestive enzymes.
71
what are zymogens?
Inactive forms of digestive enzymes
72
when and how do zymogen become active?
in the lumen of the intestinal tract by proteolytic enzymes
73
what are two types of zymogens?
trypsinogen and chymotrypsinogen
74
what's the structure of the liver composed of?
hepatic duct and cystic duct