Lecture 27 - Bone Healing & Grafting Flashcards Preview

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Flashcards in Lecture 27 - Bone Healing & Grafting Deck (22)
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1

What are the 2 types of bone healing?

Primary and secondary

2

In primary healing, bone forms _____.

directly

3

What are the units of bone that are involved in remodeling?

Haversian units

4

What is secondary healing?

Intramembranous or endochondral ossification

5

What forms in secondary healing and what is it made of?

Callus;

Cartilage, fibrocartilage

6

Secondary bone healing requires _____.

blood supply (intramedullary or temporary extra-osseous)

7

What is a graft

Transfer of living tissue

8

What is an autograft?

Tissue from the same individual

9

What is an allograft?

Same spp, different individual

10

What is a xenograft?

different spp

11

What types of bones are used for grafts?

Cancellous, cortical, combo

12

What are 5 examples of things that can have a bone graft?

1. Craniofacial reconstruction

2. Cysts, non-unions, intercalary defects

3. Spine fusion

4. Segmental defect repair

5. Prosthetic implant fixation

13

What is osteogenesis?

Transfer of living cells

14

What is osteoinduction?

Induction of cells to become bone

15

What is osteoconduction?

Scaffold for bone cells

16

What is osteopromotion?

improving mechanical or biological moevement

17

What is the "gold standard" of bone replacement?

Autogenous cancellous bone

18

What are the 4 aspects of bone regeneration?

Osteogenesis, osteoinduction, osteoconduction, osteopromotion

19

What is the morbidity of using autogenous cancellous bone as a graft?

low in animals

20

What are indications to use an autogenous cancellous bone graft?

Bone defects, slow healing fractures, non-unions/delayed unions, open fractures with bone loss, spinal fusions, arthrodesis, bone cysts

21

What are harvest locations?

Proximal humerus, iliac wing, distal femur, proximal tibia, rib

22

What are some substitutes to grafts?

Calcium phosphates, bioactive glass, coral, calcium sulfate, demineralized bone matrix