Liver, Pancreas and Gall Bladder Flashcards Preview

Histology > Liver, Pancreas and Gall Bladder > Flashcards

Flashcards in Liver, Pancreas and Gall Bladder Deck (35):
1

functions of liver

oxidise triglycerides to produce energy
synthesise plasma proteins
synthesise cholesterol
carbohydrates + proteins -> fatty acids and triglycerides
regulate blood glucose concentration
synthesise plasma proteins
detoxification of metabolic waste products, drugs and toxins
storage of glycogen, vitamins and iron
synthesis and secretion of bile

2

liver capsule

collagenous connective tissue covered by a layer of mesothelial cells derived from the peritoneum

3

liver made up of segments called

lobules

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compnents of the portal triad

hepatic portal vein, hepatic artery and bile ductules

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main cells of the liver

hepatocytes

6

blood flow channels are called

sinusoids

7

ultrastructure of sinusoids

lined by endothelial cells
narrow space between these lining cells and hepatocytes

8

Space between hepatocytes and lining cells is

space of Disse

9

what projects into the space of disse

microvilli of the hepatocytes

10

epithelium of the sinusoid is

fenestrated

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parenchyme of the liver is supported by

reticular fibres along with some type I collagen

12

hepatic stellate cells

modfied fibroblasts that make connective tissue
store vitamin A

13

Kupffer cells

remove particulate matter drom the blood and help remove worn out red blood cells

14

what is bile

an alkaline solution containing water, ions, phospholipids, bilirubin and bile salts

15

gall bladder structure

- lined by simple columnar epithelium with a bruch border backed by a lamina propria of loose connective tissue rich in blood and lymphatic vessels
- a coat of smooth muscle and an outer collagenous layer of adventitia
- has folded mucosa when empty

16

Functions of gall bladder

Stores bile
modifies stored bile within it

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how is bile modified by gall bladder

Na and Cl ions from bile pumped into spaces between adjavcent epithelial cells which causes water to follow

18

what happens to the water removed from bile

carried away by lymphatic vessels

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where does the gall bladder deliver bile to

the duodenum

20

what causes gall bladder to contract

nervous control and release of hormones

21

Pancreas is both an

Exocrine and endocrine gland

22

Exocrine pancreas

Secretes digestive juices containing proteases, lipases, nucleases, amylases

23

How do digestive enzymes enter the duodenum

Through the pancreatic duct

24

Endocrine pancreas

Consists of small, scattered islands of tissue called Islets of Langerhans which produce insulin and glucagon

25

Microscopic endocrine pancreas

Numerous serous acini and ducts

26

Why are the cells of the endocrine pancreas basophilic

As the have large amounts of rER

27

What form are the enzymes of the endocrine pancrease produced

Inactive proenzymes

28

Where are pancreatic enzyme activated and how

In the duodenum and peptidase converts trypsinogen into the active form of trypsin

29

The pancreas has a thin connective tissue

Capsule with connective tissue septa that split the pancreas into lobules

30

Basal cells of the pancreas are typically

Basophillic

31

Why are the basal cells basophilic

They have lots of rER

32

The apical part of the pancreas is usually

Eosinophillic due to the presence of zymogen granules

33

Intercalated ducts

Extend into the acini
Within the acini they are called centroacinar cells

34

The main pancreatic duct joins the

Common bile duct

35

The pancreatic and common bile duct enter into the

Ampulla of vater