Liver, Pancreas and Gall Bladder Flashcards

(35 cards)

1
Q

functions of liver

A
oxidise triglycerides to produce energy
synthesise plasma proteins
synthesise cholesterol
carbohydrates + proteins -> fatty acids and triglycerides
regulate blood glucose concentration
synthesise plasma proteins
detoxification of metabolic waste products, drugs and toxins
storage of glycogen, vitamins and iron
synthesis and secretion of bile
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2
Q

liver capsule

A

collagenous connective tissue covered by a layer of mesothelial cells derived from the peritoneum

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3
Q

liver made up of segments called

A

lobules

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4
Q

compnents of the portal triad

A

hepatic portal vein, hepatic artery and bile ductules

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5
Q

main cells of the liver

A

hepatocytes

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6
Q

blood flow channels are called

A

sinusoids

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7
Q

ultrastructure of sinusoids

A

lined by endothelial cells

narrow space between these lining cells and hepatocytes

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8
Q

Space between hepatocytes and lining cells is

A

space of Disse

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9
Q

what projects into the space of disse

A

microvilli of the hepatocytes

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10
Q

epithelium of the sinusoid is

A

fenestrated

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11
Q

parenchyme of the liver is supported by

A

reticular fibres along with some type I collagen

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12
Q

hepatic stellate cells

A

modfied fibroblasts that make connective tissue

store vitamin A

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13
Q

Kupffer cells

A

remove particulate matter drom the blood and help remove worn out red blood cells

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14
Q

what is bile

A

an alkaline solution containing water, ions, phospholipids, bilirubin and bile salts

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15
Q

gall bladder structure

A
  • lined by simple columnar epithelium with a bruch border backed by a lamina propria of loose connective tissue rich in blood and lymphatic vessels
  • a coat of smooth muscle and an outer collagenous layer of adventitia
  • has folded mucosa when empty
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16
Q

Functions of gall bladder

A

Stores bile

modifies stored bile within it

17
Q

how is bile modified by gall bladder

A

Na and Cl ions from bile pumped into spaces between adjavcent epithelial cells which causes water to follow

18
Q

what happens to the water removed from bile

A

carried away by lymphatic vessels

19
Q

where does the gall bladder deliver bile to

20
Q

what causes gall bladder to contract

A

nervous control and release of hormones

21
Q

Pancreas is both an

A

Exocrine and endocrine gland

22
Q

Exocrine pancreas

A

Secretes digestive juices containing proteases, lipases, nucleases, amylases

23
Q

How do digestive enzymes enter the duodenum

A

Through the pancreatic duct

24
Q

Endocrine pancreas

A

Consists of small, scattered islands of tissue called Islets of Langerhans which produce insulin and glucagon

25
Microscopic endocrine pancreas
Numerous serous acini and ducts
26
Why are the cells of the endocrine pancreas basophilic
As the have large amounts of rER
27
What form are the enzymes of the endocrine pancrease produced
Inactive proenzymes
28
Where are pancreatic enzyme activated and how
In the duodenum and peptidase converts trypsinogen into the active form of trypsin
29
The pancreas has a thin connective tissue
Capsule with connective tissue septa that split the pancreas into lobules
30
Basal cells of the pancreas are typically
Basophillic
31
Why are the basal cells basophilic
They have lots of rER
32
The apical part of the pancreas is usually
Eosinophillic due to the presence of zymogen granules
33
Intercalated ducts
Extend into the acini | Within the acini they are called centroacinar cells
34
The main pancreatic duct joins the
Common bile duct
35
The pancreatic and common bile duct enter into the
Ampulla of vater