Endocrine System Flashcards

(67 cards)

1
Q

Functions of endocrine system

A

Maintain body homeostasis, help the body react to stress and regulate growth and development, including sexual development

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2
Q

How does the endocrine system achive its functions

A

Through the production and secretion of hormones

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3
Q

What are the main types of hormones produced by the endocrine system

A

Protein and glycoprotein, small peptide, derivatives of amino acids and steroids derived from cholesterol

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4
Q

What does the endocrine system consist of

A

Major endocrine organs, organs with partial endocrine roles and the diffuse endocrine system

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5
Q

What is the origin of most endocrine tissue

A

Epithelial

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6
Q

Some major endocrine glands

A

Pituitary, hypothalamus, pineal, thyroid, parathyroid, thymus, adrenal glands, pancreas and gonads

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7
Q

Why is the pituitary known as the master gland

A

As its hormones regulate the activity of many other endorine glands

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8
Q

Where is the pituitary located

A

Sella turcica of the sphenoid bone

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9
Q

Another name for the pituitary

A

Hypophysis

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10
Q

What are the two lobes of the pituitary

A

Anterior/adenohypothysis and posterior/neurohypophysis

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11
Q

What is the posterior lobe developed from

A

Downwards growth of the hypothalamus

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12
Q

What attaches the posterior lobe to the hypothalamus

A

Pituitary stalk

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13
Q

What does the anterior lobe form from

A

An upwards pocket of epithelium in the roof of the oral cavity called Rathke’s pouch

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14
Q

What controls the secretion from the anterior pituitary

A

Hormones released from the hypothalamus

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15
Q

How are the hormones from the hypothalamus delivered to the anterior pituitary

A

In high concentrations through they hypothalamic-hypophyseal portal system

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16
Q

What hormones does the pituitary secrete

A

Oxytocin, ADH, growth hormones, prolactin, gonadotropins, ACTH and TSH

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17
Q

What are the hypothamic hormones that regulate the anterior pituitary

A

Growth-releasing hormone, somatostatin, thyrotropic-releasing hormone, corticotrophin-hormone, alopanine and gonadotropin-releasing hormone

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18
Q

What does the anterior pituitary consist of

A

Packed secretory cells interspersed with fenestrated endothelium-lined vascular sinuses

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19
Q

What are the cells of the anterior pituitary

A

Acidophils, basophils and chemophobes

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20
Q

What are acidophils and basophils known as collectively

A

Chromophils

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21
Q

What does the posterior pituitary consist of

A

Axons of nerve cells in the suraoptic and paraventricular nuclei of the hypothalamus

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22
Q

What are the special glial cells within the posterior pituitary

A

Pituicytes

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23
Q

What are the swellings in the axons of the posterior pituitary

A

Herring bodies

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24
Q

What are herring bodies

A

Aggregations of oxytocin or ADH

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25
What is the portion of the pituitary between the anterior and posterior lobes
Pars intermedia
26
What is the pars intermedia
The remnants of the lumen of Rathke pouch
27
What is contained within the pars intermedia
Follicles that contain a colloid
28
What is the functional unit of the thyroid gland
Thyroid follicle
29
What is the thyroid follicle
A spherical space lined by epithelial cells that are low cuboidal when inactive
30
What regulates the basal cell metabolism and heat production
T3 and T4
31
What are C cells
Cells adjacent to the follicle cells | They are within the basal lamina that surrounds the follicle
32
What do C cells produce
Calcitonin
33
What function does calcitonin have
Inhibits osteoclast activity and lowers blood calcium
34
What are C cells derived from
Neural crests
35
What are the parathyroid glands
Four oval glands on the posterior surface of the thyroid gland
36
What do the parathyroid glands produce
Parathyroid hormone
37
Function of parathyroid hormone
Increases serum calcium by stimulating the release of calcium from bone, increasing renal calcium absorption and increasing calcium absorption from the gut
38
What are the 3 cells within the parathyroid glands
Principle/chief cells, oxyphils and occasional adipose cells
39
Chief cells
Small, lightly stained cells with dark, central nuclei | Secrete PTH
40
Oxyphils
Larger eosinophil cells Appear at puberty and become more numerous with age Have large numbers of mitochondira
41
What surrounds the parathyroid gland
Connective tissue capsule
42
What forms the adrenal cortex
Epithelial cells
43
What forms the adrenal medulla
Neural crest cells
44
What surrounds the adrenal glands
A thick capsule with connective tissue trabeculae extending inwards through the cortex
45
Layers of the adrenal cortex
Zona glomerulosa Zona fasciculata Zona reticularis
46
What type of hormones are secreted by the zona granulosa
Mineralocorticoids
47
Function of mineralocorticoids
Electrolyte and fluid homeostasis
48
What is the main mineralocorticoid
Aldosterone
49
Function of aldosterone
Promotes Na+ retention in the distal convoluted tubule of the kidney
50
What type of hormones does the zona fasciculata produce
Glucocorticoids
51
Unction of glucocorticoids
Involved in many aspects of metabolism
52
What is the main glucocorticoid produced
Cortisol
53
Control of secretion of cortisol
ATCH from the anterior pituitary
54
What type of hormones does the zona reticularis produce
Sex hormones
55
What does the adrenal medulla reinforce
The actions of the sympathetic nervous system at times of stress
56
Cells of the adrenal medulla
Slightly basophilic and arranged in cords and nests | Consist of granules of adrenaline and noradrenaline
57
What type of gland is the pancreas
Both exocrine and endocrine
58
What does the endocrine pancreas consist of
Scattered islands of tissue called islets of Langerhan
59
Blood supply of the islets of Langerhan
Have a rich blood supply
60
Secretory cells of the pancreas
Lightly stained and spherical-clustered cells
61
Principle cells within the pancreatic islets
Insulin secreting cells, glucagon secreting cells and somatoststin secreting cells
62
Function of insulin secreting cells
Lowering of blood glucose
63
Function of glucagon secreting cells
Elevation of blood glucose
64
Function of somatostatin secreting cells
Inhibit insulin and glucagon secretion
65
What is an antibody
A identifiable marker on or in a specific cell
66
What hormone do the testes produce and what cell produces it
Testosterone and the Leydig cells
67
What hormones do the ovaries produce
Oestrogen and progesterone