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Flashcards in Lower respiratory tract infections Deck (56)
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31

common carriers of strep pneumo

preschool kids

32

transmisison of strep pneumo

person to person in close contact
NOT school or work

33

predisposing factors to strep pneumo

defective antibody production
defective complement
neutrophil deficiency
defective bacteria clearance
previous viral infection

34

treatment of strep pneumo

penicillin
macrolides
quinolones
vancomcin

35

ermB

high level of resistance to ALL macrolides

36

mefA

low level resistance to some macrocodes

37

causes of atypical pneumonia

mycoplasma pneumoniae
leginella pneumonae

38

mycoplasma pneumonaia features

no cell wall
small
slow growing
special media

39

myocplasma pneumoniae causes

bronchopneumonia

40

transmission of mycoplasma pneumoniae

spread via respiratory droplets

41

symptoms of mycoplasma pneumoniae

sore throat
cough
fever

42

diagnosis of mycoplasma pneumoniae

clinical presentation- no sputum production

43

CXR of mycoplasma pneumoniae

uni/bilateral patchy infiltrate in lower lobes

44

treatment of mycoplasma pneumoniae

macrolides
tetracyclines
fluoroquinolones

45

features of leginella pneunominphilia

gram neg bacillus
thermophilic
grows on special media
found in ponds

46

transmission of legionella

inhalation of infected aerosoles

47

symptoms of legionella pneumonia

flu
watery diarrea
vomitting
diarrhea
low O2--> lethargy, confusion

48

life cycle of legionella

infects the macrophage
type 4 secretion system inserts proteins that block formation of phagolysosomes
bacteria replicate in the vesicle
ppGpp increases as nutrients decrease which triggers transcription of genes for release

49

diagnosis of legionella

antibody staining or ELISA on urine- misses cases
culture- slow
CXR- patchy dsitribution

50

treatment of legionella

macrolides
tetracyclines
quinolones

51

nosocomial early onset

52

nosicomial late onset

>4 days
gram neg bacilli
staph aureus

53

VAP risk factors

prolonged hospitalization
repeated intubations
endotracheal or NG tube
prior antibiotic therapy
stress, ulcer prophylaxis
supine position

54

microaspiration

most common
colonized secretions from upper airways get into lower lung areas
gram neg bacilli
staph aureus

55

macroaspiration

infection with esophageal or gastric material
bacteria condenses in tube and forms biofilm
pieces break off and get into lung

56

symptoms of VAP

fever
leukocytosis
purulent sputum
new lobar filtrate