Lymphatic And Immune Systems Flashcards

(92 cards)

1
Q

3 purposes of lymphatic system

A

1) protect
2) maintain fluid levels
3) absorb fat

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2
Q

What do primary lymphoid organs produce?

A

Lymphocytes

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3
Q

What are the 2 primary lymphoid organs?

A

1) bone marrow
2) thymus

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4
Q

Name secondary lymphoid organs

A

Adenoids
Tonsils
Lymph nodes
Spleen
Digestive system

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5
Q

What is lymph?

A

Clear, watery fluid

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6
Q

How much fluid leaks out of capillaries daily?

A

20 liters

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7
Q

How much of 20 liters per day is returned back to the blood by the lymphatic system daily?

A

17 liters

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8
Q

What happens to the 3 liters per day of interstitial fluid that isn’t returned to the blood?

A

Stays in tissue

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9
Q

Where are lymphatic vessels found?

A

Around capillaries

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10
Q

Where does right lymphatic duct drain??

A

Right subclavian veins to superior venae cava

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11
Q

Where is Cysterna chyli

A

Abdomen

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12
Q

Where does Left thoracic duct drain

A

Left subclavian, jugular or angle between the two

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13
Q

Where are lacteals found

A

Small intestine villi

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14
Q

What kind of lymphatic collecting vessels follow veins

A

Superficial

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15
Q

What kind of collecting lymphatic vessels follow arteries?

A

Deep

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16
Q

What acts like a little filter and is packaged with immune cells?

A

Lymph nodes

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17
Q

How big are lymph nodes

A

mm-cm

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18
Q

Where are major lymph nodes in upper body?

A

1) cervical
2) posterior mediastinal
3) axilla
4) cubital

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19
Q

Where are lymph nodes in lower body?

A

1) Lumbar
2) iliac
3) Inguinal
4) popliteal

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20
Q

What is progression of lymph structures

A

Capillary
Vessel
Trunk
Duct

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21
Q

What 2 things help move lymph through system?

A

1) smooth muscle in vessels reacting to arterial pulsing
2) skeletal muscle

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22
Q

What are the 2 parts of immunity?

A

1) innate
2) adaptive

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23
Q

Which type of immunity acts immediately and is non-specific?

A

Innate

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24
Q

What are the 2 types of barriers of innate immune system?

A

1) physical
2) chemical

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25
What are examples of physical barriers in innate immune system?
Skin Cilia Mucus
26
Examples of chemical barriers in innate immunity
1) lysozymes in tears 2) stomach acids 3) micro flora
27
What type of tissue is lymphoid tissue made of
Reticular connective
28
What is largest secondary lymph organ
Spleen
29
What is main function of spleen?
Filter blood
30
What part of spleen is similar to lymph nodes to track pathogens and activate immune reaction?
White pulp
31
What part of spleen recycles red blood cells?
Red pulp
32
Where are T-cells matured
Thymus
33
What do T-cells fight primarily
Viruses and cancer
34
What do B cells often fight
Bacteria
35
What 3 cells do tonsils contain
Dendritic T cell B cell
36
What fights non-specific infections, is fast, causes fever and has no memory?
Innate immunity
37
What has memory, has to be primed, takes a few weeks to form and fights specific antigens
Adaptive immunity
38
What is hematopoiesis?
Formation of blood cells
39
What is the parent immune cell made in bone marrow?
Multipotent hematopoietic stem cell
40
What 2 cells are produced from the parent stem cell?
Myeloid Lymphoid
41
What do myeloid cells mainly make?
RBCs, platelets, some WBCs
42
If made by myeloid cell, what part of immune system is it?
Innate
43
What is made by lymphoid cells?
Lymphocytes
44
What part of immunity is made in lymphoid cell
Adaptive
45
What one innate cell is made by lymphoid cell?
Natural killer (NK)
46
Myeloid cells make
1) neutrophils 2) eosinophils 3) basophils 4) mast cells 5) monocytes
47
Most numerous Phagocytic cells; “bouncer cell”
Neutrophils
48
Phagocytic cell that fights parasites and also cause inflammation and histamine release
Eosinophil
49
Least abundant myeloid cell that is a non-phagocyte and triggers allergic response
Basophil
50
Non-Phagocytic myeloid that lives in tissue and is stationary
Mast cell
51
When monocyte is activated by infection, becomes what?
Macrophage or dendritic cell
52
True/False: Monocytes, macrophages and dendritic cells are phagocytic
True
53
How does cisterna chyli pull lymph toward heart
Suction
54
Where do monocytes circulate
Only in blood
55
Where do macrophages circulate
In tissue only, not in blood
56
What is similar to a neutrophil but lasts longer?
Macrophage
57
What is often related to chronic inflammation?
Macrophages
58
Where are dendritic cells found?
Blood, lymph and tissue
59
2 Non-phagocytic granulocytes that circulate in blood
Basophils Eosinophils
60
3 lymphoid cells
B cell T cell NK cell
61
Adaptive immune response is broken down into these two categories
Active Passive
62
2 types of active adaptation
Humoral Cell-mediated
63
In what type of active adaptation do B cells secrete antibodies indirectly?
Humoral
64
When T cells send chemicals to signal neutrophils and macrophages to kill invaders, what type of active adaptation is this called?
Cell-mediated
65
What are the two types of T cells?
1) Helper 2) cytotoxic
66
What type of T cells release chemicals that attract other immune cells?
Helper
67
What type of T cells do the work of killing pathogens?
Cytotoxic
68
True/false: Helper T cells can differentiate between our cells and foreign ones
True
69
What do cytotoxic cells use to poke holes in cell membranes?
Perforin
70
9 small proteins that trigger a cascade of immune response enzymatically
Complement System
71
First protein of Compliment System
C1
72
Three outputs of complement system
1) chemotoxins 2) opsonins 3) membrane attack complex (MAC)
73
Seeks out specific antibody produced by B-cell and recruits other proteins to launch attack.
C1 protein in complement system
74
When T cells release chemotaxins, what happens?
Macrophages and neutrophils release free radicals
75
Puts a protein marker on a pathogen
Opsonin
76
Creates a big hole in a cell membrane (similar to perforin)
Membrane attack complex (MAC)
77
What part of the immune system is the compliment system?
Innate response
78
What part of immune system is inflammatory process?
Innate
79
4 goals of inflammatory process?
1) respond 2) eliminate 3) clear 4) repair
80
3 types of inflammation
Acute, sub-acute, chronic
81
Triggers of inflammatory process
External and internal
82
What are mechanisms of inflammatory response
Vascular - construct/dilate, capillary permeability Cellular
83
Clear, thin, watery interstitial fluid
Serous
84
Blood exudate also called
Sanguinous
85
Pink, thin, water exudate
Serosanguinous
86
Thick, opaque, pus exudate
Purulent
87
A lot of mucus, upper respiratory exudate
Catarrhal
88
Tissue repairing exudate; also in epicarditis
Fibrinous
89
5 signs of inflammation
1) red 2) hot 3) pain 4) swelling 5) loss of function
90
What lymphocytes produce antibodies?
B-cells
91
Immune cells in lymph nodes that trap and eat pathogens
Dendritic
92
To activate T lymphocytes and start an immune response, you need a/an…
Antigen presentation