Meningitis,Joints,Sepsis Flashcards

-Meningitis -Prosthetic Joint -Sepsis

1
Q

T/F: Encephalitis is usually caused by a virus.

A

True

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2
Q

MCC encephalitis virus.

A

Arboviruses

  • St. Louis and California (especially La Crosse)
  • Transmitted by mosquitos
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3
Q

Viruses ass. w/ encephalitis. (6)

A
  • Arbovirus (MC)
  • HSV1
  • HHV6
  • Mumps
  • Measles
  • VZV
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4
Q

HSV1 Encephalitis features.

  • Brain region affected
  • Histology
  • CSF findings
A
  • Anterior temporal lobes
  • Necrosis/Hemorrhage
  • RBCs in CSF
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5
Q

Common cause of viral encephalitis in children.

A

HHV6 (exanthem subitum)

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6
Q

Primary amebic meningoencephalitis.

A

Naegleria fowleri

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7
Q

Granulomatous amebic encephalitis causes. (2)

A
  • Acanthamoeba spp.

- Balmuthia mandrillaris

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8
Q

MCC of Aseptic meningitis.

-Seasons

A

Enteroviruses (All age groups)

-Summer and Fall

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9
Q

MCC of aseptic meningitis in Winter and Spring.

A

Lymphocytic choriomeningitis virus (LCM)

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10
Q

Bacterial Meningitis:

-Neonates (4)

A
  • Group B strep
  • E. coli
  • Klebsiella
  • Listeria monocytogenes
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11
Q

Bacterial Meningitis:

-Infants, young kids, young adults (3)

A
  • Neisseria meningitidis (MC)
  • S. pneumoniae
  • H. influenzae type B*

*H. influenzae was MC until immunization

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12
Q

Bacterial Meningitis:

-Adults (2)

A
  • S. pneumoniae (MC)

- N. meningitidis

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13
Q

Bacterial Meningitis:

-Southeast Asia (MC)

A

-Streptococcus suis

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14
Q

Bacterial Meningitis:

-AIDS

A
  • S. pneumoniae (MC)
  • M. tuberculosis (basilar meningitis)
  • Cryptococcus neoformans
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15
Q

Bacterial Meningitis - CSF findings:

  • WBCs
  • Glucose
A
  • Marked Leukocytosis (Neutrophils)

- Decreased Glucose (Marked)

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16
Q

Aseptic (Viral) Meningitis - CSF findings:

  • WBCs
  • Protein
  • Glucose
A
  • Mild Leukocytosis (lymphocytes)
  • Mild-Moderate Increase in Protein
  • Glucose WNL

*Similar findings seen in Encephalitis

17
Q

Herpes Encephalitis - CSF findings:

A
  • Bloody CSF
  • Very High Protein
  • Low glucose
18
Q

MCC of prosthetic joint infections.

A

Coagulase negative staphylococci

19
Q

Rare organism commonly seen in Shoulder prostheses.

A

Propionibacterium acnes

20
Q

Prosthetic Joint Infection - Organisms:

-Early (<3 months) (2)

A
  • S. aureus

- Gram Neg bacilli

21
Q

Prosthetic Joint Infection - Organisms:

-Delayed (3-24 months) (2)

A
  • Coag Negative staph

- P. acnes

22
Q

Sepsis - Definintion.

A

Systemic inflammation with a known source of infection

23
Q

Laboratory markers of systemic inflammation. (11)

A
  • Respiratory Alkalosis
  • Hypoxemia
  • Abnormal WBC count
  • Increased CRP
  • Increased IL-6
  • Increased Procalcitonin
  • Increased Lactate
  • Hyperglycemia
  • Altered Coagulation paramets
  • Thrombocytopenia
  • Hyperbilirubinemia
24
Q

Systemic inflammation without an infectious source is called what?

A

SIRS

systemic inflammatory response syndrome

25
Q

Most common causes of Neonatal Sepsis. (2)

A
  • E coli

- Groub B streptococcus

26
Q

Clinical syndromes and Most CommonCausative agents:

-Rocky Mountain Spotted Fever

A

Rickettsia rickettsii

27
Q

Clinical syndromes and Most CommonCausative agents:

-Whooping cough

A

Bordetella pertussis

28
Q

Clinical syndromes and Most CommonCausative agents:

-Viral pneumonia (Adults)

A

Influenza A (Orthomyxovirus)

29
Q

Clinical syndromes and Most CommonCausative agents:

-Osteomyelitis

A

S. aurues

30
Q

Clinical syndromes and Most CommonCausative agents:

-Hand-Foot-Mouth Disease

A

Coxsackie A

31
Q

Clinical syndromes and Most CommonCausative agents:

-Viral myocarditis

A

Coxsackie B

32
Q

Clinical syndromes and Most CommonCausative agents:

-Measles

A

Rubeola virus

33
Q

Clinical syndromes and Most CommonCausative agents:

-German Measles

A

Rebella virus

34
Q

Clinical syndromes and Most CommonCausative agents:

-Animal bite associated cellulitis

A

Pasteurella multocida