Flashcards in Micro 1 CNS Deck (18)
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1
Pleocytosis
Increased WBC in CSF
2
Myelitis
Inflammation of spinal cord
3
Meningismus
Found more in bacterial than viral meningitis
4
Brain stem involvement (ataxia and/or nystagmus)
Suggestive of Listeria
5
Kernig's sign
Hamstring spasm to protect inflamed sciatic nerve
6
Brudzinski's sign
Leg flexion in response to neck flexion
7
Highest CSF pressure
Bacterial
8
Normal CSF pressure
50-180
9
Bacterial meningitis Protein & Glucose levels
Protein > 200
Glucose < 40
10
Petechiae
Usually bacterial
11
Immune response
IgA
Complement
12
Bacterial strategies
IgA protease
Polysaccharide capsule against complement
13
Bacterial meningitis: 3 causes of brain edema
Vasogenic (increased BBB permeability)
Cytotoxic
Interstitial (obstruction of CSF flow)
14
Aseptic meningitis lab levels
Protein normal or slightly raised
Glucose unchanged
Lymphocyte dominance
15
Most common meningitis viral cause
Enterovirus
16
Most common encephalitis viral cause
HSV
17
Brain abscess triad
Fever, headache, focal neurologic deficit
18
