Flashcards in Microbiology Deck (119)
How do you know it's an anaerobe?
Gas, bad odor
What makes an adequate sputum sample?
25 leukocytes per low power field
What bug causes acute bacterial endocarditis?
Strep viridians (attacks damaged valves)
How do you diagnosed Rheumatic Fever?
Need at least 2 "SPECC"
Erythema Marginatum (red margins)
Carditis (MS>AS>TS) "MAT"
What are the only Gram - diplococci?
What is the only Gram + diplococci?
What bugs cause heart block onfections?
"Dont TeLL Chaga"
Typhoid fever (salmonella typhii)
Chagas disease (Whipple's)
What are the IgA protease bugs?
What do the IgA protease bugs cause?
Sinusitis, otitis media, pneumonia, bronchitis
What are the simple Gram-bugs?
What are the atypical (no cell wall) bacteria?
What is the only Gram + endotoxin?
What are the Gram - exotoxins?
H influenza, Bordetella Pertussis
What are the spore forming Gram + bacteria?
Bacillus anthracis, Clostridium botulinum
What bugs cause walking pneumonia?
"Come My Love for a walk?
0-2 mo: Chlamydia pn
10-30 y: Mycoplasma pn
>40 y: Legionella pn
AIDS/Premies: Pneumo Jirovecii
What causes Cryoglobulinemia?
"I AM HE"
Hep B, C
What are the Silver Stainers?
What bacteria cause diarrhea
What are the Gram - capsules?
"Some Killers Have Pretty Nice Capsules"
H influenza B
What is the Gram + Capsule?
What are the Urease + bugs?
What bugs cause Monocytosis?
What are the big Mama Anaerobes?
What bugs disrupt G proteins?
Pertussis: inhibits Gi
Cholera: Stimulates Gs
E. coli: Stimulates Gs
What bacterias causes UTIs and prostatitis?
What bug is associated w/cat scratch?
What bug is associated w/cat saliva?
WHat bug is associated w/ cat pee?
What bug is associated w/cat caca?
What disease are caused by the Ixodes Tick?
Lyme disease -bull's eye lessions
Babesiosis - hemolytic anemia
Ehrlichiosis - puncture near eye
What bug causes hospital abscesses?
Day 1-3: Staph aureus - lots of O2
Day 4-7: Strep viridans: no enzymes
Day >7: Anaerobes - PMNs
What kind of patients does Staph and Pseudomonas like to attack?
Cystic fibrosis pt
What disease have granulomas?
What disease provide malaria protection?
Sickle cell: AAs
What bug causes multiple liver abscesses?
What bug causes multiple cerebral abscesses?
What has multiple lung aneurysms?
What bugs cause Loeffler syndrome?
What is the symptom of Loeffler syndrome?
What is PIE syndrome?
Pulmonary Infiltrate w/ Eosinophilia
What disease have PIE syndrome?
Aspergillus, Loeffler's, Churg-Strauss
What disease does Coxsackie A cause?
What disease does Coxsackie B cause?
Endocarditis, DM type 1
What bugs cause Meningitis?
0-2mo: "baby BEL"
Group B strep
>2mo: Strep pneumo
10-21y/o: N. meningitidis
What are the CSF lab vales for Meningitis?
Normal glucose -> viral
What does the Hep B Core Ag tell you?
Gone before pt has symptoms (2 mo)
What does the core Ab tell you?
What does the surface Ag tell you?
What does the surface Ab tell you?
Vaccination has occurred
What does the E Ag tell you?
What does the E Ab tell you?
What antibody shows past Hep A infection?
What antibody shows current Hep A infection?
What type of people does Hep E like to infect?
Pregnant women. Asians
What is associated with Staph aureus?
Cellulitis, dairy products, gold pigment, endocarditis, styes, hordeolum (on eyelid)
What is associated with Strep pyogenes?
"LINES", ASO, hyaluronic acid capsule
What is associated with Staph epidermidis?
Central lines, VP shunts, white pigment
What is associated w/ Propionibacterium?
Acne, Progesterone=> propionic acid
What is associated w/Pateurella?
Cat/dog saliva => cellulitus w/lymphadenitis
What is associated w/Staph saprophyticus?
Female UTIs, honeymooners cystitis
What is associated w/ Hemophilus aegyptus?
Swollen eyeball w/pus
What is associated w/Francisella tularensis?
Ulcers at rabbit or deer tick bite site (Tx: Streptomycin)
What is associated with Pseudomonas aeruginosa?
Otitis externa, ecthyma granulosum, loves rubber, whirlpool folliculitis, ADP ribosylates EF-2
What is associated w/Streptococcus pneumoniae?
Otitis media, red bulging tympanic membrane
What is associated w/ Fusobacterium?
Painful mouth ulcers, gum pus, Vincents angina
What is associated w/Strep mutans?
What is associated w/ Strep viridans?
Subacute bacterial endocarditis, green pigment
What is associated w/Strep salivarius?
Cold agglutinin test
What is associated w/Strep pyogenes?
Rheumatic fever, strain 12=>PSGN
What is associated w/ Group C Strep?
What is associated w/ Corynebacyerium diphtheriae?
Chinese letters, gray pseudomembrane, suffocation, ADP ribosylates EF2, heart block, Elek test
What is associated w/ Strep pneumonia?
Gram + diplococci, rusty sputum, IgA protease, vaccine covers 23 strains
What is associated w/ H influenza?
Gram - pleomorphic rod, Factors V/X, 5 C-ribose capsule, B-type:meningitis, epiglottitis, sepsis
What is associated w/ N Catarrhalis?
Loves mucus-> attacks respiratory tract
What is associated w/ Chlamydia psittaci?
What is associated with Chlamydia pneumonia?
Staccato coughing, elementary and reticulate bodies
What is associated with Mycoplasma pneumonia?
Bullous myringitis, ground glass CXR, P1 protein, erythema multiforme
What is associated w/ Legionella pneumonia?
AC ducts, silver stains lung, CYEA, pontiac fever, Legionnaire's pneumonia
What is associated with Pnuemocystis Jiroveciinia?
AIDS, premies, rusty sputum, silver stains lung, ^ LDH (Tx: steroids)
What is associated with Clostridium botulinum?
Canned food, honey, inhibits Ach release, resp failure, stool toxin (Tx: Penicillin)
What is associated with Clostridium tetani?
Rusty nail wounds, inhibits Gly release, resp failure, risus sardonicus, tennis, racquet shape
What is associated with Bordetella pertussis?
Whooping cough, ADP ribosylates Gi
What is associatedw/Bacillus antracis?
Black eschar, woolsorter's lung disease, D-Glu, boxcar-like spore (Tx: Ciprofloxacin)
What is associated with H pylori?
What is associated with Salmonella?
Raw chicken & eggs, tutles, rose typhoid spots, H2S, sickle cell osteomyelitis
What is associated w/ Campylobacter jejuni?
Raw chicken & eggs, very bloody diarrhea, inactivated by gastric juice, Guillain-Barre, seagull -shape
What is associated with clostridium perfringes?
Holiday ham & turkey, DM gas gangrene, soil/feces
What is associated w/ Bacillus cereus?
Fried rice, pre-formed toxin
What is associated with Listeria monocytogenes?
Raw cabbage, hot dogs, spoiled milk, migrant workers => heart block, meningitis, abortions
What is associated w/ Vibrio parahaemolyticus?
What is associated with Actinomyces?
Face fistulas, sulfur granules
What is associated w/ Vibrio vulnificus?
Raw oysters, cellulitis in swimmers cuts
What is associated with Shigella?
Day care outbreaks => seizures, destroys 60 S ribosome, infects M cells
What is associated with Vibrio Cholera?
Rice water diarrhea, ADP ribosylates Gs
What is associated w/ Clostridium difficile?
Explosive diarrhea= pseudomembranous colitis
What is associated with Yersinis enterolitica?
Presents like appendicitis + Reiter's, bloody diarrhea
What is associated w/ Strep bovis?
Colon cancer, black pigment
What is associated with Clostridium septicum?
What is associated with ETEC?
Traveler's=> rice-water diarrhea
What is associated with EHEC?
Hemmorrhagic=> renal failure
What is associated w/ EIEC?
Inflammatory=> loose stool
What is associated w/ EPEC?
Pathogenic=> newborn diarrhea
What is associated w/ E. coli?
Raw hamburger, ADP ribosylates Gs, verotoxin, HUS
What is associated w/ Proteus mirabilis?
Staghorn calculus, UTI (Tx: Norfloxacin)
What is associated w/Klebsiella pneumonia?
Alcoholics, currant jelly sputum, UTI lung fissure
What is associated w/ Staph saprophyticus?
Young & college girls UTIs
What is associated with N meningitides?
DIC, pili, releases toxin in log phase
What is associated with Brucella?
farmers/vet, spiking fever 5x/day, animal placentas
What is associated w/ R. rikettsii?
Ticks=> Rocky mountain spotted fever
What is associated w/ R. akari?
Mites=> fleshy papules
What is associated w/ R typhi?
Fleas, starts in armpit
What is associated w/ R. prowazekii?
Lice, starts on body
What is associated w/ R tsutsugamushi?
Mites=> scrub typhus
What is associated with Coxiella burnetti?
Dusty barn=> Qfever
What is associated w/ Yersinia pestis?
Rats, fleas=> bubonic plague
What is associated with Bartonella henselae?
Cat scratch => single painful lymph node, silver stains
What is associated w/ bacteroides fragilis?
Post-op bowel abscess, grows in blood clots
What is associated w/ Chlamydia trachomatis?
Neonatal inturned eyelashes/cornea ulcers