Microbiology Part 1 Flashcards Preview

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Flashcards in Microbiology Part 1 Deck (33)
1

Phagocytic cells of the immune system

neutrophils, monocytes, macrophages

2

present antigen to T cells,
starts as Monocyte

macrophages

3

can inactivate pathogens

natural killer cells

4

3 main types of T cells

killer T, helper T and Regulatory T

5

triggers target to commit "suicide"

killer T cells

6

help in antigen recognition and regulation

helper T cells

7

keeps other T cells under control

regulatory T cells

8

target of antibody and T cells

antigen

9

where antibody binds on antigens

epitope

10

present antigen for T cells to see

Histocompatibility Complex Proteins

11

found on surface of most cells,
iinforms Killer T cells of whats goin on INSIDE cell

Class 1 HCP

12

made by antigen presenting cells (macrophages), informs helper T cells of problems OUTSIDE cells

class 2 HCP

13

plants the "kiss of death"

antibody (opsonization)

14

very fast system of 20 different proteins made by the liver consisting of 3 different pathways

Complement system

15

3 different pathways of the Complement System

classical (depends of antibodies)
Alternative (antibody independnt)
Lectin activation path

16

mannose binds lectin leading to the attraction of phagocytes

lectin activation pathway (complement system)

17

T cell mediated hypersensitivity

Type IV

18

caused by proteins from mold or plant spores

hay fever

19

caused by dust mites, cockroaches, rodents, and household pets

asthma

20

allergic reponse cells that degranulate

mast cells

21

self-reactive T cells,
myelin sheaths destroyed,
CNS

multiple sclerosis

22

Activated T cells can cross the BBB

multple sclerosis

23

90% women,
inflammation of lungs, arthritis, kidney damage, hair loss, paralysis and convulsions, caused by breakdown of B and T cells that make IgG antibodies

Lupus

24

Thymic tissue missing,
Bubble boy,
No T cells

DiGeorge syndrome

25

no T or B cells

Severe Combined Immunodeficiency Syndrome

26

Pneumocystis carinii

AIDS

27

Sabin

live and attenuated virus

28

Salk

Kills virus

29

Generates memory helper T and B cells but not memory killer T cells

Noninfectious vaccines (salk)

30

vaccine with weakened form of microbe,
produce memory killer T cells

attenuated (most vaccines)

31

introduces a single gene from pathogenic microbe into virus,
called a Trojan horse,
doesn't cause disease

carrier vaccine

32

active immunity

live (attenuated) or killed viruses

33

passive immunity

occurs naturally