MIDTERMS -part 2 - trypanosoma- BLOOD AND TISSUE FLAGELLATES Flashcards

(59 cards)

1
Q

specie of trypanosoma that is considered as brucei complex

A

trypanosoma gambiense
trypanosoma rhodesiense

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2
Q

mode of transmission for genus trypanosoma

A

vector bite
ingestion of infection feces of intermediate host by definitive host
entrance/inoculation of parasite through abrasion or break skin

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3
Q

insect vectors of genus trypanosoma

A

glossina flies
reduviid bug

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4
Q

glossina flies is also called as

A

tse tse flies

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5
Q

tse tse flies or glossina flies is for what species of trypanosoma

A

gambiense and rhodiense

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6
Q

reduviid bug is for what specie of trypanosoma

A

cruzi

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7
Q

species of trypanosoma that are called as african trypanosomiasis

A

brucei complex - gambiense and rhodiense

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8
Q

species of trypanosoma that iscalled as american trypanosomiasis

A

trypanosoma cruzi

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9
Q

other names of trypanosoma crzi

A

Schozitrypanum
cruzi

Trypanosoma
escomele

Trypanosoma
triatomae

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10
Q

geographical distribution of trypanosoma cruzi

A

Central & South
America

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11
Q

Aside from the
given mode of
transmission,
Trypanosoma cruzi
can be transmitted
through ___ that is specific only for Trypanosoma cruzi

A

blood
transfusion.

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12
Q

disease associated with trypanosoma cruzi

A

South American
Trypanosomiasis

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13
Q

general term of disease associated with trypanosoma cruzi infection

South American
Trypanosomiasis

A

Sleeping sickness

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14
Q

Sleeping sickness is scientifically or particularly known as

A

chagas’ disease

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15
Q

what is the clinical feature of the disease associated with trypanosoma cruzi

A

sleeping sickness

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16
Q

sleeping sickness is also called as

A

somnolence

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17
Q

2 stages of manifestation for trypanosoma for all species

A
  1. hemolymphatic
    stage
  2. meningoencephalitic
    stage
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18
Q

the common name for the insect vector of trypanosoma cruzi

A

reduviid bug

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19
Q

reduviid bug is also called as

A

Triatomid bug
Assassin bug
Kissing bug
Cone nose bug

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20
Q

riduviid bug is also called as kissing bug because?

A

–it bites the
person near the lips

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21
Q

Scientific names for
reduviid bugs:

A
  1. Panstrongylus
    megistus
  2. Triatoma infestans
  3. Rhodnius prolixus
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22
Q

Mode of transmission for trypanosoma cruzi

A
  1. Bite of reduviid bug
    which defecate at site
    of inoculation
  2. Accidental ingestion
    of bug
  3. Blood transfusion
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23
Q

infection site of stage 2 for trypanosoma disease

A

CNS

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24
Q

American
trypanosomiasis was
first described by
___ in
Brazil
in 1909

A

Carlos Chagas

25
The infection, Chagas' disease, is caused by the hemoflagellate __
Trypanosoma cruzi
26
the disease is a public health threat in most Latin American countries, although cases due to blood derivatives or blood transfusion has been reported in non-endemic regions.
chagas disease
27
trypanosoma cruzi, In blood films, it can be seen as what shape?
sickle shape, twisted, letter C, S U.
28
a stage wherein the Parasite is settling in blood or lymph
hemolymphatic stage
29
for trypanosoma cruzi, Main cause of death of the patient is
Brain infection or damage - Blockage of the artery in the heart
30
Characteristics of a reduviid bug is once it bite the human, it will _____ on the bite site containing the parasite. Thus, trypomastigote of the trypanoma is transmitted through feces not the saliva of an infected insect.
defecate
31
trypanosoma cruzi, There are times that it can contaminate ocular mucosa resulting to conjunctivitis and edema of the eyelids known as ___
Romaña's sign
32
The primary lesion of trypanosoma cruzi is in the form of ___
Chagoma
33
A nodular lesion or furuncle, usually called ____, can appear at the site of inoculation
chagoma
34
any infection of trypanosoma is crucial to diagnose and treat it as early in the ___ stage
hemolymphatic
35
mode of diagnosis for trypanosoma cruzi
1. Microscopic demonstration of parasite stained blood smear / lymphnode aspirate 2. Culture NNM medium 3. serological
36
culture used for trypanosoma cruzi
NNM or NNN
37
serological test for trypanosoma cruzi
ELISA
38
drugs for trypanosoma cruzi
Primaquine partially effective Nifurtimox acute cases = there is no entirely available drug for tx./ prevention of the disease
39
other name of trypanosoma gambiense
west African trypanosomiasis
40
geographical distribution of Trypanosoma gambiense
Central & West Coast of Africa
41
disease associated to trypanosoma gambiense is called
gambian sleeping sickness
42
common name for the vector of T. Gambiense
tse tse fly - glossina spp
43
tse tse fly or glossina species
Scientific name: 1. Glossina palpalis 2. Glossina techinoides
44
It will indicate that the recovered parasite is trypanosoma gambiense due to the presence of what granule?
volutin granule
45
trypanosoma gambiense lesions are in the form of ___, which is similar to syphilis
chancre
46
signs for trypanosoma gambiense
Winterbottom’s sign Kerandel’s sign
47
among the sign for trypanosoma gambiense which one is for the enlargement of nodes>
Winterbottom’s sign
48
among the sign for trypanosoma gambiense which one is associated with the first stage of disease in trypanosoma?
winterbottom's sign
49
among the sign for trypanosoma gambiense which one is associated with the 2nd stage of disease in trypanosoma?
Kerandel's sign
50
among the sign for trypanosoma gambiense which one is about the delayed sensation of pain?
kerandel's sign
51
method of diagnosis for trypanosoma gambiense
1. Microscopic examination smear from lymph, blood & CSF 2. Serological test
52
the serological test for gambiense is based on the detection of
anti-trypanosome antibodies
53
2 serological test for gambiense
A. immunofluorescence test B. indirect hemagglutination tes
54
drugs for trypanosoma gambiense
Pentamidine & Suramin (very effective if given during hemolymphatic stage) Tryparsamide 2-3 grams 15-20 weeks Metarsoprol - for late stage with CNS involvement
55
a drug for trypanosoma gambiense if the late stage with cns is involve
Metarsoprol
56
habitats of trypanosoma gambiense
blood lymph nodes csf connective tissue intracellular space brain lymph channels throughout the body
57
trypanosoma is geographycally distributed to
east africa
58
based on its location, trypanosoma rhodesiense's disease is called
east african sleeping disease Rhodesian Sleeping Sickness
59
the difference in life cycle of Trypanosoma cruzi and trypanosoma brucei complex
in trypanosoma cruzi, instead of infecting salivary gland, the parasite will infect the hind gut