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PARASITOLOGY > MIDTERMS -part 2 - trypanosoma- BLOOD AND TISSUE FLAGELLATES > Flashcards

MIDTERMS -part 2 - trypanosoma- BLOOD AND TISSUE FLAGELLATES Flashcards

1
Q

specie of trypanosoma that is considered as brucei complex

A

trypanosoma gambiense
trypanosoma rhodesiense

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2
Q

mode of transmission for genus trypanosoma

A

vector bite
ingestion of infection feces of intermediate host by definitive host
entrance/inoculation of parasite through abrasion or break skin

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3
Q

insect vectors of genus trypanosoma

A

glossina flies
reduviid bug

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4
Q

glossina flies is also called as

A

tse tse flies

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5
Q

tse tse flies or glossina flies is for what species of trypanosoma

A

gambiense and rhodiense

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6
Q

reduviid bug is for what specie of trypanosoma

A

cruzi

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7
Q

species of trypanosoma that are called as african trypanosomiasis

A

brucei complex - gambiense and rhodiense

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8
Q

species of trypanosoma that iscalled as american trypanosomiasis

A

trypanosoma cruzi

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9
Q

other names of trypanosoma crzi

A

Schozitrypanum
cruzi

Trypanosoma
escomele

Trypanosoma
triatomae

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10
Q

geographical distribution of trypanosoma cruzi

A

Central & South
America

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11
Q

Aside from the
given mode of
transmission,
Trypanosoma cruzi
can be transmitted
through ___ that is specific only for Trypanosoma cruzi

A

blood
transfusion.

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12
Q

disease associated with trypanosoma cruzi

A

South American
Trypanosomiasis

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13
Q

general term of disease associated with trypanosoma cruzi infection

South American
Trypanosomiasis

A

Sleeping sickness

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14
Q

Sleeping sickness is scientifically or particularly known as

A

chagas’ disease

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15
Q

what is the clinical feature of the disease associated with trypanosoma cruzi

A

sleeping sickness

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16
Q

sleeping sickness is also called as

A

somnolence

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17
Q

2 stages of manifestation for trypanosoma for all species

A
  1. hemolymphatic
    stage
  2. meningoencephalitic
    stage
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18
Q

the common name for the insect vector of trypanosoma cruzi

A

reduviid bug

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19
Q

reduviid bug is also called as

A

Triatomid bug
Assassin bug
Kissing bug
Cone nose bug

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20
Q

riduviid bug is also called as kissing bug because?

A

–it bites the
person near the lips

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21
Q

Scientific names for
reduviid bugs:

A
  1. Panstrongylus
    megistus
  2. Triatoma infestans
  3. Rhodnius prolixus
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22
Q

Mode of transmission for trypanosoma cruzi

A
  1. Bite of reduviid bug
    which defecate at site
    of inoculation
  2. Accidental ingestion
    of bug
  3. Blood transfusion
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23
Q

infection site of stage 2 for trypanosoma disease

A

CNS

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24
Q

American
trypanosomiasis was
first described by
___ in
Brazil
in 1909

A

Carlos Chagas

25
Q

The infection,
Chagas’ disease,
is caused by the
hemoflagellate
__

A

Trypanosoma cruzi

26
Q

the disease is a
public health
threat in most Latin
American countries,
although cases due
to blood derivatives
or blood transfusion
has been reported
in non-endemic
regions.

A

chagas disease

27
Q

trypanosoma cruzi,
In blood films, it can be
seen as what shape?

A

sickle shape,
twisted, letter C, S U.

28
Q

a stage wherein the Parasite is settling in
blood or lymph

A

hemolymphatic stage

29
Q

for trypanosoma cruzi, Main cause of death of the patient
is

A

Brain infection or
damage - Blockage of the artery
in the heart

30
Q

Characteristics of a reduviid bug is
once it bite the human, it will _____ on the bite site
containing the parasite. Thus,
trypomastigote of the trypanoma
is transmitted through feces not
the saliva of an infected insect.

A

defecate

31
Q

trypanosoma cruzi, There are times that it can
contaminate ocular mucosa
resulting to conjunctivitis and
edema of the eyelids known as
___

A

Romaña’s sign

32
Q

The primary lesion of trypanosoma cruzi is in the form
of ___

A

Chagoma

33
Q

A nodular lesion or
furuncle, usually called
____, can appear
at the site of
inoculation

A

chagoma

34
Q

any infection of trypanosoma is crucial to diagnose and
treat it as early in the
___ stage

A

hemolymphatic

35
Q

mode of diagnosis for trypanosoma cruzi

A
  1. Microscopic demonstration
    of parasite stained blood
    smear / lymphnode aspirate
  2. Culture NNM medium
  3. serological
36
Q

culture used for trypanosoma cruzi

A

NNM or NNN

37
Q

serological test for trypanosoma cruzi

A

ELISA

38
Q

drugs for trypanosoma cruzi

A

Primaquine
partially effective
Nifurtimox acute
cases

= there is no
entirely available
drug for tx./
prevention
of the disease

39
Q

other name of trypanosoma gambiense

A

west African
trypanosomiasis

40
Q

geographical distribution of Trypanosoma gambiense

A

Central & West
Coast
of Africa

41
Q

disease associated to trypanosoma gambiense is called

A

gambian sleeping sickness

42
Q

common name for the vector of T. Gambiense

A

tse tse fly - glossina spp

43
Q

tse tse fly or glossina species

A

Scientific name:
1. Glossina palpalis
2. Glossina techinoides

44
Q

It will indicate
that the
recovered
parasite is
trypanosoma
gambiense

due to the presence of what granule?

A

volutin granule

45
Q

trypanosoma gambiense

lesions are in the form of ___,
which is similar to syphilis

A

chancre

46
Q

signs for trypanosoma gambiense

A

Winterbottom’s sign
Kerandel’s sign

47
Q

among the sign for trypanosoma gambiense
which one is for the enlargement of nodes>

A

Winterbottom’s sign

48
Q

among the sign for trypanosoma gambiense
which one is associated with the first stage of disease in trypanosoma?

A

winterbottom’s sign

49
Q

among the sign for trypanosoma gambiense
which one is associated with the 2nd stage of disease in trypanosoma?

A

Kerandel’s sign

50
Q

among the sign for trypanosoma gambiense
which one is about the delayed sensation of pain?

A

kerandel’s sign

51
Q

method of diagnosis for trypanosoma gambiense

A
  1. Microscopic examination
    smear from lymph, blood &
    CSF
  2. Serological test
52
Q

the serological test for gambiense is based on the detection of

A

anti-trypanosome antibodies

53
Q

2 serological test for gambiense

A

A. immunofluorescence test
B. indirect hemagglutination
tes

54
Q

drugs for trypanosoma gambiense

A

Pentamidine &
Suramin (very
effective if given
during
hemolymphatic
stage)

Tryparsamide 2-3
grams 15-20
weeks
Metarsoprol - for
late stage with
CNS involvement

55
Q

a drug for trypanosoma gambiense if the late stage with cns is involve

A

Metarsoprol

56
Q

habitats of trypanosoma gambiense

A

blood
lymph nodes
csf
connective tissue
intracellular space brain
lymph channels throughout the body

57
Q

trypanosoma is geographycally distributed to

A

east africa

58
Q

based on its location, trypanosoma rhodesiense’s disease is called

A

east african sleeping disease

Rhodesian Sleeping
Sickness

59
Q

the difference in life cycle of Trypanosoma cruzi and trypanosoma brucei complex

A

in trypanosoma cruzi, instead of infecting salivary gland, the parasite will infect the hind gut

PARASITOLOGY (10 decks)

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