Flashcards in MOD 9.1 - Neoplasia 2 Deck (6):
What is metastasis?
The development of secondary malignant growths at a site distant from the primary site of cancer
How can metastasis travel to other sites?
- Through blood
- Through lymph
- Grow directly into the surrounding tissue
What is invasion of a metastasis?
- Cells pass through the basement membrane and extra cellular matrix
What is tumour burden?
- The number of cancer cells, size of a tumour or amount of cancer in the body
- Invasion + metastasis = ↑ tumour burden
Why does tumour burden not increase with benign tumours?
They don't metastasise