MODULE 5 Flashcards by Gabrielle Sodusta

Arrange the following: From most to least
dipole characteristics
I. Debye forces
II. London forces
III. Keesom forces
A. II, I, III
B. III, I, II
C. I, II, III
D. III, II, I

III, I, II

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Which of the following terms is used to describe the solubility of a substance if 800 mg of the solute can be dissolved in 95 mL water
A. Slightly soluble
B. Soluble
C. Sparingly soluble
D. Practically insoluble

Slightly soluble

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Lacrimal fluid has an isotonicity values
corresponding to that of NaCl solution with
the strength of
A. 0.1%
B. 9.0%
C. 1.0%
D. 0.9%

0.9%

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The buffer equation is also known as
A. Noyes-whitney equation
B. Arrhenius
C. Henderson-Hasselbalch
D. Van’t hoff

Henderson-Hasselbalch

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Convert 37.5 degrees Celsius to Fahrenheit
A. 98.6 degrees Fahrenheit
B. 99.5 degrees Fahrenheit
C. 100.4 degrees Fahrenheit
D. 100.3 degrees Fahrenheit

99.5 degrees Fahrenheit

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Crystal symmetry of Urea
A. Cubic
B. Tetragonal
C. Hexagonal
D. Rhombic

Tetragonal

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Compute for the E-value of Zinc Chloride
(MW = 135.9) with an Liso of 5.1.
A. 0.46
B. 0.64
C. 453
D. 1.22

0.64

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Determine the heat required to increase the internal energy and to perform work.
A. Specific heat
B. Heat potential
C. Entropy
D. Enthalpy

Enthalpy

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Which of the following is a colligative property?
A. Osmotic pressure
B. Boiling point
C. Freezing point
D. Vapor pressure

Osmotic pressure

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Which of the following statements about the rate of dissolution of a solid API into an aqueous biological environment is true?

A. Increasing the particle size decreases the dissolution rate resulting in a quicker onset of action
B. Increasing the particle size increases the dissolution rate resulting in a quicker onset of action
C. Increasing the particle size increases the dissolution rate resulting in a slower onset of action
D. Increasing the particle size decreases the dissolution rate resulting in a slower onset of action

Increasing the particle size decreases the dissolution rate resulting in a quicker onset of action

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Official method of the USP for determining specific gravity

A. Floatation method
B. Baume method
C. Westphal balance
D. Pycnometer method

Pycnometer method

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Mesh number

A. Number of square openings per linear inch
B. Number of square inches per linear opening
C. Number of linear openings per square inch
D. Number of linear inches per square openings

Number of square openings per
linear inch

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Contact angle exhibited by complete nonwetting

A. 0 degree
B. 90 degrees
C. 180 degrees
D. 360 degrees

180 degrees

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Isometric (isochoric)
A. Constant heat
B. Constant temperature
C. Constant volume
D. Constant pressure

Constant volume

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n optical microscopy, this is the longest tangent line that can be measured in a particle

A. Martin diameter
B. Feret diameter
C. Projected area diameter
D. Longest diameter

Feret diameter

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An autonomic particle counter that uses electric resistance to determine the size of the particle

A. HIAC Royco
B. Coulter counter
C. Gelman
D. Abbe

Coulter counter

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Range of HLB value in the Griffin scale for anti-foaming agents
A. 1-3
B. 3-8
C. 8-16
D. 16-18

1-3

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Flow system that shows a yield value
A. Plastic
B. Pseudoplastic
C. Dilatant
D. Newtonian

Plastic

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Select the INCORRECT statement about Surfactants.
A. Wetting agents aid in attaining intimate contact between solid particles and liquids.
B. Detergents reduce the surface tension and aid in wetting the surface and the dirt.
C. Surface-active agents with HLB values 3-6 are greatly lipophilic and produce water-in-oil emulsion.
D. The usual range of HLB values for surfactants used as solubilizing agents is between 1-3.

The usual range of HLB values for surfactants used as solubilizing agents is between 1-3.

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The gram-molecular volume of gas at STP is equal to:

A. 1.0 L
B. 2.24 L
C. 22.4 L
D. 22.4 mL

22.4 L

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Section of Quality Control Division
A. Microbiological section
B. Plant Inspection section
C. Specification & Assay
D. AOTA

AOTA

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Consists of the products which have been bottled, stripped, packed, but not yet labeled

A. In-process section
B. Dispensing pharmacist
C. Inventory control
D. Production control

In-process section

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Responsibility of an organization to determine the systems, facilities, & written procedures:

A. Technological element
B. Aesthetic element
C. Quality Control
D. Quality Assurance

Quality Assurance

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Variations between suppliers of the same substance for:

A. Materials
B. Machines
C. Methods
D. Man

Materials

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Aging & Improper care is one cause of variation of: A. Materials B. Machines C. Methods D. Man

Man

Non-compliance to cGMP can result in the following: A. Quality variation B. Contamination C. Mix-ups and errors D. AOTA

AOTA

Kills all living organism including spores & viruses: A. Steam under pressure B. Bacterial filtration C. Chemical sterilization D. NOTA

Steam under pressure

The Inspection & Checking section of QC is responsible for: A. Sampling of raw materials B. Chemical Assaying C. Testing sterility of products D. Doing pyrogen test

Sampling of raw materials

Quarantined materials delivered in the warehouse are: A. Subject to test & assay B. Rejected C. Releasable to production department D. In-process products

Subject to test & assay

Aggregates of powders which adhere or bond to each other to form larger particles: A. Powders B. Microcapsules C. Pellets D. Granules

Granules

Caused by poor mixing of the granulation: A. Weight variation B. Double impression C. Sticking D. Chipping

Weight variation

The ff. excipients impart satisfactory compression characteristics to the tablet formulation except: A. Glidant B. Disintegrant C. Lubricant D. Anti-adherents

Disintegrant

Which of the ff. additives in parenterals reduce the pain of injection in areas with nerve endings? A. Buffers B. Tonicity adjusters C. Chelating agents D. NOTA

Tonicity adjusters

Weight variation test is carried out in: A. 10 tabs B. 20 tabs C. 30 tabs D. 40 tabs

20 tabs

Method of tablet manufacture for easily compressible or adhesive ingredients is: A. Direct compression B. Dry method C. Wet method D. Slugging

Direct compression

A type of tablet coating which is a modified form of film coating differing only in the size of the particles to be coated and the method used: A. Compression coating B. Enteric coating C. Marumerization D. Microencapsulation

Microencapsulation

Improperly sealed ampoules should be tested for: A. Particulate matter B. Pyrogen C. Bacteria D. Leak

Leak

The most inert grade of stainless steel used for high grade products: A. SS 304 B. SS 316 C. SS 3004 D. SS 3016

SS 316

The method for the preparation of compressed tablet wherein the granulation is formed by compacting large masses of the mixture & subsequently crushing and sizing these pieces into smaller granules A. Dry granulation B. Wet granulation C. Direct compression D. AOTA

Dry granulation

Poorly manufactured tablets with extended on the edge or periphery, this defect is called: A. Mottling B. Picking C. Capping D. Whiskering

Whiskering

Which of the following package types is tamper evident by design? A. Plastic bottles B. Aerosol container C.Ointment jars D.Sealed boxes/cartons

Aerosol container

Which of the following regulation is responsible for classifying drugs into two-OTC medicines and prescription drugs? A. Durham-Humphrey Amendment of 1952 B. The Federal Food, Drug, And Cosmetic Act of 1938 C. Comprehensive Drug Abuse Prevention and Control Act of 1970 D.None of the above

Durham-Humphrey Amendment of 1952

Which type of segregation occurs when the finer, lighter particles remain suspended in air longer and do not settle as quickly as the larger or denser particles? A.Segregation B.Fluidization C.Sifting D.Dusting

Dusting

Which of the following method of particle size determination is done by measuring terminal settling velocity of particles through a liquid medium and is computed by Stoke's Law? A. Microscopy B. Sedimentation rate C. Laser holography D. Cascade Impaction E. Light Scattering

Sedimentation rate

Which of the following distinctive looking capsules has both ends tapered? A. Snap fit B. Coni-snap C. Spansules D. Pulvules E. Kapseals

Spansules

What is the smallest capsule size? A.5 B. 3 C.1 D.0 E. 000

Which of the following ingredients is used in the preparation of sugar-free chewable tablets? A. Xylitol B. Lactose C. Mannitol D. Dextrose E. Sucrose

Xylitol

Which of the following film coating problems refers to flaking of larger amounts of film fragments from the tablet surface? A. Picking B. Peeling C. Orange Peel Effect D. Mottling E. Bridging

Peeling

Aquaphor is an example of what type of ointment base? A. Hydrocarbon base B. Absorption base C. Water soluble base D.Water removable base

Absorption base

What is the concentration of water in glycerogelatins? A. 15% B. 40% C. 35% D. 10%

35%

Which of the following is added to the base of the suppository to prolong drug release? A. Citric acid B. Beeswax C. Alginic acid D. Yellow wax

Alginic acid

Which of the following refers to eutectic mixtures of mono-, di-, and triglycerides derived from natural vegetable oils, each type having slightly different properties? A. Fattibase B. Suppocire OSI C. Wecobee W D. Witepsol H15

Suppocire OSI

What is the relative term of solubility of a compound if 1 gram is dissolved in 150 ml solvent? A. Soluble B. Sparingly soluble C. Slightly soluble D. Insoluble E. Very soluble

Slightly soluble

Which mixing category is frequently encountered when highly viscous fluids are being processed? A. Bulk transport B. Turbulent mixing C. Laminar mixing D. Molecular diffusion

Laminar mixing

What is the activity of an emulsifying agent with an HLB value of 8-18? A. Antifoaming B. Wetting agent C. Emulsifier D.Detergents E. Solubilizers

Emulsifier

Which of the following methods of size reduction is also known as jet milling or micronizing? A. Dry milling B. Micropulverization C. Fluid energy grinding D. Spray drying

Fluid energy grinding

Which of the following is used for patients who have suffered a heavy loss of fluid and electrolyte? A. Irrigating solution B. Replacement therapy C. Maintenance therapy D. Enteral nutrition

Replacement therapy

What inert gas is used in the airspace during packaging of injectable products? A. Oxygen B. Nitrogen C. Helium D. Carbon dioxide

Nitrogen

Formaldehyde is an example of what type of ingredient in biological products? A. Stabilizer B. Residual inactivating ingredient C. Residual cell culture D.Adjuvant

Residual inactivating ingredient

What animal is used to prepare heterologous sera? A. Snake B. Mice C. Pig D. Monkey E. Horse

Horse

What is the active ingredient in vitrasert implant? A. Histrelin B. Ganciclovir C. Goserelin D. Leuprodile

Ganciclovir

Which of the following is indicated for initiation and/or continuation of cervical ripening in patients at or near term when there is medical or obstetrical indication for labor induction? A. Progestasert system B. Dinoprostone vaginal insert C. Estring D. Crinone gel

Dinoprostone vaginal insert

Which of the following consist of a flexible impermeable diaphragm surrounded by a sealed layer containing an osmotic agent that is enclosed within a semipermeable membrane? A. Films B. Mucoadhesive system C. Osmotic pump D. Medicated gums

Osmotic pump

Initial application for certificate of medical device registration for class B will have a validity of how many years? A.1 year B.3 years C.5 years D.10 years

5 years

Which of the following is NOT included in the documentary requirements for application of notification and registration? A. Notarized application form B. Copy of letter of Authorization C. A government-issued certificate attesting to the status of the manufacturer with regard to the competence and reliability of the personnel and facilities. D. None of the above

None of the above

All the following are cosmetic products, EXCEPT: A. Chemical Peeling Products B. Make-Up Powders C. Skin Wash Products D. Hair Dyes E. None of the above

Chemical Peeling Products

Cosmeceutical refers to cosmetic products that have medicinal or drug-like benefits. Cosmeceutical is a legal term recognized by the FDA. A.Only statement 1 is correct B.Only statement 2 is correct C.Both statements are correct D.Neither of the statement is correct

Only statement 1 is correct

All the following are examples of chemical sunscreens, EXCEPT: A. Avobenzone B. Homosalate C. Zinc Oxide D. Oxybenzone

Zinc Oxide

A type of hair dye which adheres to the outside of hair fibers and partially penetrate the cuticle layers, making the hair dye longer lasting. A.Temporary B.Demi-permanent C.Semi-permanent D.Permanent

Semi-permanent

What is referred to as fairy dust and is added to a formula at a low level for the primary purpose of getting to put the ingredient name on the label? A.Functional ingredients B.Aesthetic modifiers C.Claim ingredients D.Drug actives

Claim ingredients

CIR stands for: A.Cosmetic Ingredient Repository B.Cosmetic Ingredient Review C. Cosmetic Ingredient Regulation D.Cosmetic Ingredient Rules

Cosmetic Ingredient Review

Which of the following is referred to as the negative list? A. ACD Annex VI B. ACD Annex VII C. ACD Annex II D. ACD Annex IV

ACD Annex II

This is part of the ASEAN Cosmetic Directive Technical Documents, EXCEPT: A. ASEAN Microbial Limit B. ASEAN Heavy Metal Limit C. ASEAN Botanical Safety Assessment Guidance Document D. ASEAN Guidelines on GMP for Traditional Medicines / Health Supplements

ASEAN Guidelines on GMP for Traditional Medicines / Health Supplements

Cannabis sativa is considered a banned ingredient in cosmetic products based on RA 9165. Cell, tissues, or products of human origin are allowed to be a part of cosmetic products in the Philippines. A. Only statement 1 is correct B. Only statement 2 is correct C. Both statements are correct D. Neither of the statement is correct

Only statement 1 is correct

Which of the following is found on the label of products that has been observed to have serious adverse events and potential safety hazards? A.Precaution B.Contraindication C.Warning D.Hazard

Warning

Which of the following refers to an audit that may be triggered by consumer complaints or results found on samples found in the market? A.Internal Audit B.Ad-hoc Audit C.Routine Audit D.None of the above

Ad-hoc Audit

Which of the following test is required only for raw materials of botanical origin? A. Physical specifications B. Mutagenicity C. Pesticide level D. Absence of Annex II ingredients beyond unavoidable traces E. None of the above

Pesticide level

Done to ensure that the product is notified and compliant to current labelling requirements and guidelines. A.Post-evaluation B.Product verification C.Advertisement monitoring D.Consumer/product complaint

Product verification

The following are activities under PMS, EXCEPT: A.Product Verification B.Issuance of FDA Advisory C.Post-evaluation D.Notification Application E.None of the above

Notification Application

“The Philippine Pharmacy Act” was approved and signed into Law by President Benigno Aquino III on: A. July 23, 2016 B. May 23, 2016 C. July 21, 2016 D. May 21, 2016

July 21, 2016

This order gives comprehensive guidelines on the registration of Pharmaceutical Products to be consistent with RA 6675 A. AO 220 B. AO 42 C. AO 67 D. AO 90 E. AO 56

AO 67

It is a drug which contains no amount of, or a different active ingredient or less than 80% of the active ingredient it purports to possess, as distinguished from an adulterated drug including reduction or less of efficacy due to expiration: A. Counterfeit drug B. New drug C. Investigational drug D. Tried and tested drug E. Ethical drugs

Counterfeit drug

Revised rules and regulations to implement Dispensing Requirements under the Generics Act of 1988: A. AO 63 B. AO 62 C. AO 42 D. AO 55 E. AO 56

AO 63

The Universally Accessible Cheaper and Quality Medicines Act of 2008 is known as RA: A. RA 9257 B. RA 9502 C. RA 9165 D. RA 9205 E. RA 9527

RA 9502

RA 9502 is an act providing for cheaper and quality medicines, amending the Intellectual Property Code also known as: A. RA 8205 B. RA 8293 C. RA 8203 D. RA 8295

RA 8293

RA 9994, The Expanded Senior Citizens Act of 2010 was signed and enacted into law by President Gloria Macapagal Arroyo on: A. February 10, 2010 B. July 27, 2009 C. February 15, 2010 D. July 15, 2009

February 15, 2010

Grounds for suspension of LTO of Drug Establishment: A. Lapses for record keeping of invoices B. Sale of antibiotics without batch certification C. Selling of misbranded drugs D. Serious repeated or rampant violation of existing laws E. Lapses in record keeping of CPR

Lapses for record keeping of invoices

Absence of Pharmacist in a drugstore on three inspections by BFAD inspector is a ground: A. Cancellation of the prof license of the said pharmacist B. Suspension of the LTO C. Revocation of the LTO D. Permanent Closure E. Temporary Closure

Temporary Closure

It means a system of words or other systems arbitrary used to represent words: A. Code B. Secret keys C. Secret clues D. Cipher E. Coding

Code

The Code of Ethics for the Pharmaceutical Profession was promulgated by the Board of Pharmaceutical Examiners on: A. February 28, 1924 B. February 8, 1924 C. February 18, 1924 D. NOTA

February 28, 1924

The book kept for the purpose of recording the sale of violent poisons should be preserved for a period of: A. 1 year B. 2 years C. 4 years D. 5 years E. 3 years

5 years

The amount of shabu subjected to life imprisonment to death and fine ranging from 500,000 pesos to 10M pesos. A. 500 g B. 10 g C. 50 g D. 40 g E. 20 g

50 g

Duration of the conduct of examination in determining the genuineness and authenticity of the product by Bureau A. 10 working days B. 20 working days C. 16 working days D. Within 24 hours

20 working days

A drug product prescribed which is not registered with BFAD is considered a type of A. Impossible Rx B. Violative Rx C. Erroneous Rx D. Coded Rx E. Registered Rx

Impossible Rx