Flashcards in Module 5 (part of test 2) Deck (88):
HTN is a _______ ______ BP?
What is a normal BP?
What is HTN-2?
What is Pre-HTN?
What is HTN-1?
Anti-HTN drugs act on what body systems?
Anti-HTN drugs decrease ______, ______ output, and peripheral vascular _______?
What is the NORMAL resting cardiac output?
Your BP is regulated by what body systems?
What is the functional unit of the kidney?
What are the 3 main functions of the kidney?
What were the FIRST drugs used in the treatment of HTN?
What was the PROTOTYPE Diuretic?
Diuretics increase the ________ production and inhibit the _______ in the distal tubules?
What are the 3 classes of diuretics?
What are 3 side effects of Diuretics?
What is the primary diuretic used to treat HTN?
Thiazides act in the _____ _____ of the kidney to inhibit ______?
Why do patients taking Thiazides have to take a potassium supplement?
Because they cause Hypokalemia
Are Thiazides safe for Diabetics? Why/Why Not?
No- Causes Hyperglycemia
Thiazides can cause ________ which would affect pts. with Gout?
Thiazides can cause an increase in someones total ______
What common OTC drug can interfere with Thiazides?
NSAID's cause rapid _______ in pts. using Thiazides?
What dosage of Epinephrine can we give someone who is on a Thiazide Diuretic?
.04mg (cardiac dose)
Epinephrine can cause _______ ________ on a pt. who is taking Thiazide Diuretics?
What are the 2 common Thiazide Medications?
What kind of Diuretic is the MOST effective?
One down side to Loop Diuretics is that they cause severe _______ loss and ________ _______?
Loop Diuretics are great in pts. with _______ because they can cause rapid _____?
Congestive Heart Failure (CHF)
Loop diuretics inhibit NaCl reabsorption in what areas of the kidney?
loop of henle
Loop diurectics cause a hypo______ which in turn causes decreased release of _____ by the ______?
What was the PROTOTYPE Loop Diuretic?
What Medications can inhibit Lasix?
What kind of Diuretic is a "puny" one with a "K" catching ability?
Potassium-Sparing Diuretics inhibit ____ reabsorption with a reduction of K _____
What is the MOST important potassium-sparing diuretic medication?
Do we have to restrict Epi use in LA with potassium-sparing drug use?
Beta-Blocking Drug names usually end in?
Beta Blockers block the action of _____ and ____ and inhibit the ____-__-_____ response of the SNS?
Non-Specific Beta-Blockers decrease the ___ and _____ of cardiac contraction?
altering contraction forces
Non-Specific Beta Blockers have a ___ inotropic effect?
What are the 2 common Non-Specific Beta Blocking drugs?
Which of the 2 Non-Specific Beta Blockers works the BEST?
Do we have to restrict Epi use in LA with Non-selective Beta Blockers?
Yes- give cardiac dose
What are 2 common side effects of non-specific beta blocking drugs?
What receptors do SELECTIVE Beta Blockers act on?
Beta 1 (heart)
What are the 2 common Selective Beta Blocking Drugs?
Do we have to restrict Epi use in LA with Selective Beta Blocking Drugs?
Yes- give cardiac dose
Alpha 1 Blockers cause vaso______ therefore decreasing _____
Alpha 1 Blockers are also used in the tx. of?
BPH (benign prostatic Hypertrophy)
What OTC drugs can affect the kidneys Na excretion when mixed with an Alpha 1 Blocker?
An Alpha 2 Blocker prevents ______ from being released at the heart which leads to a ______ of the blood vessels?
What common Alpha 2 Blocker is used in the treatment of ADHD also?
* also can tx menopause, nicotine, and narcotic withdrawal
In teh 1980's What medication was used in the treatment of ANGINA?
Calcium Channel Blockers
Calcium Channel Blockers are now the MOST widely used drug of choice to tx?
Calcium Channel Blockers decreases the ______ and ______ of the heart as well as the demand for ______?
Calcium Channel Blockers inhibit the influx of Calcium into the ____ and ______muscle which relaxes the ______ to decrease BP?
What is the most common Calcium Channel Blocking Medication?
A small amount of people may experience what oral symptom while taking Calcium Channel Blockers?
When your BP increases the kidneys excrete ____ which decreases the ____ _____ and ______ ______?
What is produced and secreted by the kidney in response to a decrease in renal blood flow?
Renin initiates the production of ________
Angiotensin 2 is a ____ which causes _____?
vasoconstriction of all blood vessels
What kind of drugs inhibit the secretion and production of Renin?
What is the most common ACE-inhibitor Medication?
What are 2 common oral side effects of ACE- inhibitors?
Angioedema of lips/face/tongue
What medications are used to prevent and treat Coronary Ischemias and Chest Pain?
What are the 3 types of drugs used to treat Angina Pectoris?
Ca Channel Blockers
Non-selective/selective Beta Blockers
Nitrates act ______ on the heart?
Nitrates relax _______ muscle and dilate the ______ ________ which increases the amount of ______ in the blood?
What is the PROTOTYPE Nitrate Drug?
Nitroglycerin is administered _______ because of its rapid onset?
The side effects of Nitroglycerin are _____ and are due to?
What is the term given to an inability of the ventricles to pump enough blood to meet the demands?
A Healthy heart has good _______, ______, and _____
What side of the heart fails first in Cardiac Failure?
What is the most common type of drug used to treat Congestive Heart Failure?
What is the Cardiac Glycoside PROTOTYPE drug?
Glycosides have a _______ therapeutic index?
(toxic and therapeutic dose are very close )
Glycosides increase the _____ and ______ of a contraction which decreases ______ because of the increased efficiency of the heart?
How do Glycosides enhance the contractility of the heart?
by increasing the Ca Concentration
What are some common side effects of Glycosides?
gag reflex/salivation increased
Arrhythmias (at toxic level)
What 2 drugs increase the blood levels of Digoxin in 10% of pts?
What is a common Sodium channel blocking drug used to treat arrhythmias?
What is a common potassium channel blocking drug used to treat arrhythmias?
Cordarone ( amiodarone)