Module 7 (part of test 3) Flashcards Preview

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Flashcards in Module 7 (part of test 3) Deck (48):
1

The endocrine system is a ______ gland that distributes hormones _______ via the _____ system?

ductless
through body
vascular (blood)

2

What is the most important application of endocrine drugs?

replacement therapy

3

Endocrine system drugs can either affect the _____ or ______ of the hormones?

secretion
synthesis

4

What gland releases hormones that stimulate the pituitary gland?

hypothalamus

5

What endocrine gland is the MASTER gland?

Pituitary

6

A thyroid ANTAGONIST hormone _____ serum thyroid levels?

lowers

7

What was the initial therapy for hyperthyroidism?

Beta Blockers

8

What drug used in hyperthyroid disorders is used to KILL part of the gland?

Radioactive Iodine

9

What do patients have to do AFTER radioactive iodine treatment?

take thyroid supplements for life

10

What hyperthyroid drug is known to cause leukopenia and liver damage?

PTU- propylthiouracil

11

Tapazole is _______ times more potent than PTU and is used in ________ treatment because it interferes with _______?

10
hyperthyroidism
iodine uptake

12

What type of thyroid disorder is easier to treat? Hyper or Hypo?

hypo

13

What is the drug of choice to treat hypothyroidism?

Synthroid

14

Synthroid is a synthetic _____ that is similar to the natural one?

T4

15

What hypothyroid drug requires daily dosing and is harder to monitor?

Cytomel

16

What hypothyroid drug has synthetic T4 and T3 and is therefore controversial?

Thyrolar

17

______ is the name of a natural thyroid hormone that comes from pig, beef, or sheep's thyroids.

Armour

18

What is the problem with the Armour thyroid medication?

hard to predict and monitor

19

In order to use a oral hypoglycemic the patient must have?

some beta cells (type 2 diabetes)

20

What was the 1st oral agent used to treat type 2 diabetes? (when diet and exercise failed)

Sulfonylureas

21

What is the 1st generation PROTOTYPE oral hypoglycemic?

Diabinase-------- then.... Orinase

22

Sulfonylureas can decrease blood glucose by ______% but are most effective when ______ is controlled?

20
weight

23

What drug was the 2nd generation oral hypoglycemic?

Glucotrol

24

Glucotrol use increases the risk of ______ to the patient?

hypoglycemia

25

What NEW oral hypoglycemic, that is similar to sulfonylureas, is faster but MORE expensive?

Prandin ( a meglitinide )

26

The 1st recombinant (human) insulin was made in _______?

1982

27

Insulin is given to the patient when the ______ can't produce any/enough insulin to facilitate ________ Intake?

pancreas
glucose

28

What is a FAST-ACTING subcutaneous Anti-diabetic?

Novolog (pen)

29

What is a SHORT-ACTING subcutaneous anti-diabetic?

Humulin-R

30

What is an INTERMEDIATE-ACTING subcutaneous anti-diabetic?

Humulin-N

31

_____ is a LONG acting insulin that doesn't have to be administered as often?

Lantus

32

Do we have to use caution with epinephrine in LA with diabetic patients?

yes

33

Glucocorticoids, Mineralcorticoids, and Androgens are produced from what gland?

Adrenal Cortex

34

If we secrete NOT ENOUGH glucocorticoids our body has a bad ______/_______ response?

immune
stress

35

Aldosterone is the main ________ and is responsible for retaining ______ and eliminating _______?

mineralcorticoid
sodium
potassium

36

Addison's is due to a ______ of gluococorticoids?

hypo-secretion

37

Cushing's is due to a ________ secretion of corticosteroids?

excessive

38

Glucocorticoids deal with _______ rather than ______ treatment?

palliative
curative

39

Glucocorticoids are potent _____-______ agents that suppress _______?

anti-inflammatory
histamine

40

The corticosteroid steroid to receptor complex goes into the ______ of a cell and turns the ______ on or off?

nucleus
gene

41

A buffalo hump is a clinical sign of what disease?

Cushing's

42

Corticosteroids cause an elevated _____ ____ and a ______ resistance to infection?

Blood Glucose
decreased

43

What is a common TOPICAL corticosteroid?

hydrocortisone (cortaid)

44

What is the common IV/IM corticosteroid?

Decadron

45

Kenalog is a type of _____ corticosteroid?

aeresol

46

______ is an oral corticosteroid that can cause neoplasias?

Prednisone (detasone)

47

Inhaled corticosteroids can cause what 2 oral side effects?

candidiasis
xerostomia

48

What are the 2 GENERAL side effects of corticosteroid use?

mucosal healing is slow
more susceptible to infections (perio)