Module 7 (part of test 3)

Question 1

The endocrine system is a ______ gland that distributes hormones _______ via the _____ system?

Answer 1

ductless
through body
vascular (blood)

Question 2

What is the most important application of endocrine drugs?

Answer 2

replacement therapy

Question 3

Endocrine system drugs can either affect the _____ or ______ of the hormones?

Answer 3

secretion

synthesis

Question 4

What gland releases hormones that stimulate the pituitary gland?

Answer 4

hypothalamus

Question 5

What endocrine gland is the MASTER gland?

Answer 5

Pituitary

Question 6

A thyroid ANTAGONIST hormone _____ serum thyroid levels?

Answer 6

lowers

Question 7

What was the initial therapy for hyperthyroidism?

Answer 7

Beta Blockers

Question 8

What drug used in hyperthyroid disorders is used to KILL part of the gland?

Answer 8

Radioactive Iodine

Question 9

What do patients have to do AFTER radioactive iodine treatment?

Answer 9

take thyroid supplements for life

Question 10

What hyperthyroid drug is known to cause leukopenia and liver damage?

Answer 10

PTU- propylthiouracil

Question 11

Tapazole is _______ times more potent than PTU and is used in ________ treatment because it interferes with _______?

Answer 11

10
hyperthyroidism
iodine uptake

Question 12

What type of thyroid disorder is easier to treat? Hyper or Hypo?

Answer 12

hypo

Question 13

What is the drug of choice to treat hypothyroidism?

Answer 13

Synthroid

Question 14

Synthroid is a synthetic _____ that is similar to the natural one?

Answer 14

T4

Question 15

What hypothyroid drug requires daily dosing and is harder to monitor?

Answer 15

Cytomel

Question 16

What hypothyroid drug has synthetic T4 and T3 and is therefore controversial?

Answer 16

Thyrolar

Question 17

______ is the name of a natural thyroid hormone that comes from pig, beef, or sheep’s thyroids.

Answer 17

Armour

Question 18

What is the problem with the Armour thyroid medication?

Answer 18

hard to predict and monitor

Question 19

In order to use a oral hypoglycemic the patient must have?

Answer 19

some beta cells (type 2 diabetes)

Question 20

What was the 1st oral agent used to treat type 2 diabetes? (when diet and exercise failed)

Answer 20

Sulfonylureas

Question 21

What is the 1st generation PROTOTYPE oral hypoglycemic?

Answer 21

Diabinase——– then…. Orinase

Question 22

Sulfonylureas can decrease blood glucose by ______% but are most effective when ______ is controlled?

Answer 22

20

weight

Question 23

What drug was the 2nd generation oral hypoglycemic?

Answer 23

Glucotrol

Question 24

Glucotrol use increases the risk of ______ to the patient?

Answer 24

hypoglycemia

Question 25

What NEW oral hypoglycemic, that is similar to sulfonylureas, is faster but MORE expensive?

Answer 25

Prandin ( a meglitinide )

Question 26

The 1st recombinant (human) insulin was made in _______?

Answer 26

1982

Question 27

Insulin is given to the patient when the ______ can't produce any/enough insulin to facilitate ________ Intake?

Answer 27

pancreas | glucose

Question 28

What is a FAST-ACTING subcutaneous Anti-diabetic?

Answer 28

Novolog (pen)

Question 29

What is a SHORT-ACTING subcutaneous anti-diabetic?

Answer 29

Humulin-R

Question 30

What is an INTERMEDIATE-ACTING subcutaneous anti-diabetic?

Answer 30

Humulin-N

Question 31

_____ is a LONG acting insulin that doesn't have to be administered as often?

Answer 31

Lantus

Question 32

Do we have to use caution with epinephrine in LA with diabetic patients?

Answer 32

yes

Question 33

Glucocorticoids, Mineralcorticoids, and Androgens are produced from what gland?

Answer 33

Adrenal Cortex

Question 34

If we secrete NOT ENOUGH glucocorticoids our body has a bad ______/_______ response?

Answer 34

immune | stress

Question 35

Aldosterone is the main ________ and is responsible for retaining ______ and eliminating _______?

Answer 35

mineralcorticoid sodium potassium

Question 36

Addison's is due to a ______ of gluococorticoids?

Answer 36

hypo-secretion

Question 37

Cushing's is due to a ________ secretion of corticosteroids?

Answer 37

excessive

Question 38

Glucocorticoids deal with _______ rather than ______ treatment?

Answer 38

palliative | curative

Question 39

Glucocorticoids are potent _____-______ agents that suppress _______?

Answer 39

anti-inflammatory | histamine

Question 40

The corticosteroid steroid to receptor complex goes into the ______ of a cell and turns the ______ on or off?

Answer 40

nucleus | gene

Question 41

A buffalo hump is a clinical sign of what disease?

Answer 41

Cushing's

Question 42

Corticosteroids cause an elevated _____ ____ and a ______ resistance to infection?

Answer 42

Blood Glucose | decreased

Question 43

What is a common TOPICAL corticosteroid?

Answer 43

hydrocortisone (cortaid)

Question 44

What is the common IV/IM corticosteroid?

Answer 44

Decadron

Question 45

Kenalog is a type of _____ corticosteroid?

Answer 45

aeresol

Question 46

______ is an oral corticosteroid that can cause neoplasias?

Answer 46

Prednisone (detasone)

Question 47

Inhaled corticosteroids can cause what 2 oral side effects?

Answer 47

candidiasis | xerostomia

Question 48

What are the 2 GENERAL side effects of corticosteroid use?

Answer 48

mucosal healing is slow | more susceptible to infections (perio)