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Flashcards in MODY Deck (11)
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1

What does MODY stand for?

Mature onset diabetes of the young

2

What inheritance pattern does MODY usually follow?

Autosomal dominant

3

Is MODY insulin-dependent?

No

4

What is the age of onset of MODY?

Before age of 25

5

What are the 2 main distinct types of MODY?

Transcription factor mutations (HNF-1alpha)
Glucokinase mutation

6

At what age does glucokinase mutation related MODY onset?

Birth

7

At what age does transcription factor mutation related MODY onset?

Adolescence/young adulthood

8

Glucokinase mutation related MODY involves unstable hyperglycaemia. True/False?

False
Stable hyperglycaemia

9

Glucokinase mutation related MODY has better prognosis than transcription factor mutation related MODY. True/False?

True

10

Neonatal diabetes requires insulin treatment within the first 3 months of life. True/False?

True

11

Which drug class is good for transcription factor mutation related MODY?

Sulphonylureas