Flashcards in Ovulatory Disorders Deck (21)
How long is the normal menstrual cycle?
If someone has oligomenorrhoea, how long do menstrual cycles last?
Greater than 35 days
What is the difference between primary and secondary amenorrhoea?
Primary: never had a period before 16yrs old
Secondary: not had a period for 6mths in a person who has had a period before
What is another name for an ovulatory disorder caused by hypothalamic pituitary failure?
Which syndrome is associated with hypogonadotrophic hypogonadism?
Outline management of hypogonadotrophic hypogonadism
Stabilise weight (BMI over 18.5)
What is the most common ovulatory disease caused by hypothalamic pituitary dysfunction?
Polycystic ovarian syndrome
What is the criteria for diagnosing polycystic ovarian syndrome?
Polycystic ovaries on USS (12+ 2-9mm follicles)
Insulin resistance is commonly seen alongside polycystic ovarian syndrome. True/False?
Outline management of polycystic ovarian syndrome
Folic acid 400mcg/5mg if BMI over 30
Check if rubella immunity
By what 3 methods can ovulation be induced in polycystic ovarian syndrome?
Laparoscopic ovarian diathermy
What type of drugs are clomifene citrate and tamoxifen?
Anti-oestrogens (thus help stimulate FSH)
Is metformin useful in ovulation induction? If so, why?
Improves insulin resistance, thus reducing androgen production
What are the main risks of ovulation induction?
Possible ovarian cancer
What is another name for ovarian failure?
Oestrogen levels are low in ovarian failure. True/False?
List some causes of premature ovarian failure (menopause before age of 40)
XX gonadal agenesis
What is involved in a progesterone challenge test?
Should menstrual bleed in response to a 5-day course of progesterone to indicate normal oestrogen levels
List clinical features of polycystic ovarian syndrome
What are the 2 main anti-oestrogen drugs?