Mood Disorders Flashcards Preview

PSYCH > Mood Disorders > Flashcards

Flashcards in Mood Disorders Deck (40):
1

MDD requires 1 of these 2

depressed mood
anhedonia

2

the other diagnostic criteria is

5 or more of the second cateogry in greater than 2 weeks

3

3 associated symptoms of MDD and which one isnt common

anxiety
somatization
psychosis*

4

lifetime prevalence MDD

17%

5

MDD is the #__ cause of years lost due to disability and #___ contributer to overall health burden

1,3

6

more than ___% of suicide happens in MDD patients

60

7

leading cause of death in US

MDD

8

atypical MDD

improved moods with positive events

9

Melancholic MDD

among the most severe form

10

Psychotic MDD

include psychosis

11

catatonic MDD

immobile

12

post-partum MDD

after pregnancy

13

chronic MDD

recurrent

14

untreated episodes of depression generally last

4-6 months

15

major dysthmic disorder

depressed mood everyday for >2 years, no more than 2 months symptom free
associated with >2 symptoms

(chronic, but less symptoms)

16

dysthmic disorder and m:f prevalence

equal male to female

17

remission with dysthimic

less than 10% per year

18

risk of suicide in dysthmici

equal to or greater than MDD

19

mania/hypomanic episodes

three or four of symptoms
Four if irritable

20

mania

symptoms >1 week, significant dysfunction

21

hypomania

symtoms >4 days; limited dysfunction

22

mixed

mania+ depressive symptoms>1 week; significant dysfunction

23

Bipolar I disorder (3)

at least one manic or mixed episode

no need for prior depressive episode

more servere illness than BPII and easier to diagnose

24

BP II disorder (3)

at least one previous major depressive episode

at least one hypomanic episode

less severe than BP I; difficult to diagnose

25

Cyclothymia (4)

fluctuating minor depressive, hypomanic episodes

no prior MDD, manix, or mixed episodes

over 2 year period, no symptom free period >2 months

after 2years, BPI or BP2 may develop

26

BID prevalence

1%, men = women

27

BIID prevalence

0.5%, women > men

28

3 phases of bipolar treatment

antidepressants
antimanic
maintenance/prevention of episodes

29

5 options for mood stabilizing drugs

Lithium**
valproic acid/depakote
carbamazepine (tegretol)
lamotrigine (lamictal)--may not prevent mania; no acute effect
atypical antipsychotics

30

ECT

generalized cortical seizure induced
treatments 2-3xs per week for total 6-15 tx
50-70% remission rates

31

surgical approaches

white matter disconnection: 22-75% efficacy
TMS/rTMS-50% efficacy

32

TMS/rTMS

non-invasive technique for generating current in cortex and modulating neural network activity
daily treatments lasting about an hour; 15-30 tx
risk of seizure

33

slow rTMS

facilitate long term depression

34

fast rTMS

facilitate long-term potentiation

35

vagus nerve stimulation efective in

30-40% patients

36

DBS targets

sub-collaosal cingulate- activity goes down when responding to treatment

64% feel better

37

other targets MDD

inferior thalamic peduncle, lateral habenula

38

OCD indicated

subthalamic nucleus

39

Tourette's located

centromedian nucleus of thalamus, internal globus pallidus

40

Addictions

NA