MUST DO!

Question 1

Peripheral AD

Answer 1

Cilostazol- PDE3 inhib.
Vinpocetine
Nicergoline
Calcium dobesilate

ווין הוא פוץ אז יש לו פיאיידי

Question 2

Acute migrane attack

Answer 2

Sumatriptan selective 5HT 1D/B

Ergotamine

Question 3

Migrane prophylaxis

Answer 3

Galcanezumab
Propranolol
Verapamil
Carbamazapine inhibit VGNC
Valproate
Imipramine
Cinnarizine

Question 4

Positive iontropes

Answer 4

Digoxin
Milrinone is PDE inhib.
Levosimendan
Dobutamine

increase the strength of heart muscle contraction

Question 5

Inhibitor of fatty oxidation in the cardiac myocites

Answer 5

Trimetazidine

Question 6

Tolvaptan MOA

Answer 6

Orally active, specific V2 receptor antagonist

Question 7

Histamine receptors

Answer 7

H1- Gq Allergy

H2-Gs Stomach

Question 8

Why 1st gene antihistamine cause sedation?

Answer 8

They are lipophilic so cross BBB

Question 9

1st gene antihistamines

Answer 9

Diphenhydramine

Promethazine- promise me

Question 10

2nd gene antihistamines

Answer 10

Loratadine
Cetirizine
Dimetinden
Fexofenadin

Question 11

Immunotherapy cytotoxic

Answer 11

Cyclophosphamide
Azathiprine
Methotrexate
Leflonomide
Mycopholinic acid

Question 12

Calcineurin is for

Answer 12

Activation of T cells

Question 13

Sulfasalazine

Answer 13

PPAR gamma agonist
COX inhib.
For IBD

Question 14

Rituximab

Answer 14

Anti CD20. Reduce B cell count
B cell lymphoma
Autoimmune
Solid organ transp.

Question 15

Infliximab

Adalimumab

Answer 15

Anti TNFa

Question 16

Natalizumab

Answer 16

Inhibts T cells

For MS. Chrons

Question 17

Dupilumab

Answer 17

Anti IL4

Atopic dermatitis

Question 18

6MP is for

Answer 18

CML
Acute leukemia
RA, IBD

Question 19

Oxaliplatin is for

Answer 19

Colon cancer

Question 20

Bleomycin MOA, SE

Answer 20

Free radicals
Pulmonary fibrosis
Hyperpigmentation

For Hodgkins

Question 21

Dectinomycin is for

Answer 21

Wilms tumor

Question 22

Topo 1 inhib

Answer 22

Irinotecan for colon cancer

Question 23

Vincristine is for

Answer 23

Acute leukemia

Question 24

HER2

Answer 24

Lapatinib

Question 25

BRAFi | MEKi

Answer 25

Dabratinib | Trametinib

Question 26

Aldesleukin

Answer 26

IL2 for renal cancer

Question 27

Progestins

Answer 27

``` Medroxy-prog Drospirone Norethisterone Levonogestrel Desogestrel ```

Question 28

Anti progesterone

Answer 28

Mifepristone | Ulipristal acetate

Question 29

Contraceptive

Answer 29

Ethinylestradiol-Levonogestrel Medroxyprogesteron Levone, Dose

Question 30

Semisynthetic opiates

Answer 30

``` Hydromorphone- analgestic Oxycodone- analgestic Dihydrocodeine- Antitussive Buprenorphine- Withdrawl Nalbuphibe- Spinal Naloxone- acute toxic ```

Question 31

Synthetic opiates

Answer 31

``` Fentanyl- analgestic Tramadol- analgestic Meperidine- analgestic Loperamide Diphenoxilate Methadone Naltrexone- withdrawl ```

Question 32

NSAIDs general

Answer 32

Aspirin Colchicin Alluporinol Rasburicase

Question 33

NSAID's that are not Aspirin

Answer 33

``` Ibuprophen Indomethacin Naproxen Diclofenac- MSK Metamizole-SE agranulo Katoprofen Phenylbutazone- not safe Meloxicam COX2 ```

Question 34

Order of elim, Aspirin

Answer 34

Low- zero and than first

Question 35

Acute gaut

Answer 35

Naproxen | Cochicin- Microtubule

Question 36

Xanthine oxidase i

Answer 36

Alluporinol | Less purine metabolism

Question 37

Rasburicase

Answer 37

Uric acid into Allantoin

Question 38

Spasmolytics

Answer 38

Diazepam Baclofen Tizanidine Tolperisone

Question 39

Ketolide

Answer 39

Telithromycin

Question 40

Streptogarmins

Answer 40

Quinopristine | Daflopristine

Question 41

Polymixin

Answer 41

Colistin

Question 42

Fluroquinolone genes

Answer 42

2nd: Nor, Cipro, Ol 3: Levo 4: Moxi

Question 43

Glycopeptides

Answer 43

ze TOV Teicoplanin Oritavacin Vancomycin Bind D-ala-D-alaa

Question 44

Vanco SE

Answer 44

Red man synd

Question 45

Fosphomycin MOA

Answer 45

Inhibit NAG formation